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South Korea approves stem cell drug

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South Korea’s government drug agency cleared the way Thursday for commercial sales of what it called the world’s first approved medicine using stem cells collected from other people.

Cartistem, developed by Seoul-based Medipost, will help regenerate knee cartilage using stem cells developed from newborns’ umbilical cord blood, the Korea Food and Drug Administration said.

“Cartistem is… the world’s first approved allogeneic (taken from different individuals of the same species) stem cell drug, that can offer new opportunity for treatment of patients with degenerative arthritis,” the administration said in a statement.

Medipost said 27 billion won ($23.8 million) from private investors and government funds had been invested to develop Cartistem since 2001. The drug can be injected into a patient’s knees via surgery.

Clinical trials have been under way in the United States since last year, the statement said.

Two of the world’s top 10 drugmakers are in talks to seek a worldwide licence to make the drug, a Medipost spokesman told AFP, adding that final trials involving a large number of people would likely begin in the US in 2015 (…)

Cartistem, developed by Seoul-based Medipost, will help regenerate knee cartilage using stem cells developed from newborns’ umbilical cord blood, the Korea Food and Drug Administration said.

“Cartistem is… the world’s first approved allogeneic (taken from different individuals of the same species) stem cell drug, that can offer new opportunity for treatment of patients with degenerative arthritis,” the administration said in a statement (…)

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Adult Stem Cells Rebuild Broken Jawbone

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Stem Cell Research Brings About Another Miracle

Korean doctors have apparently regrown a patient’s jawbone using the patient’s own Adult Stem Cells in yet another amazing miracle that Adult Stem Cell research has brought us.

An 18 year old Korean boy who had to have most of his jawbone and his teeth removed due to a tumor was the lucky recipient of this fantastic stem cell research victory.

The young man, who had been suffering confidence problems due to his appearance (missing his jawbone and teeth) is very happy now after the Adult Stem Cells worked their magic and regrew his jawbone so he looks normal in appearance now.

Process of Stem Cells

  1. Adult Stem Cells were taken from the man’s bone marrow
  2. They were then multiplied and “coached” into becoming an osteoblast- a cell responsible for bone formation
  3. The new Adult Stem Cells were injected into the “damaged” area around the man’s jaw
  4. 6 months-1 year the stem cells grow new bone to fill in the gap left when the jawbone and teeth were removed
  5. Man’s looks better, has more confidence, happier

Stem Cell Case Study Presented at Conference

The results of the trial were published in the British medical journal BMC Medicine and it was also presented at the Korean Association of Oral and Maxillofacial Surgeons annual meeting (Those silly Maxillofacial surgeons must have forgotten my invitation)

Another Case of Adult Stem Cell Research Working Magic

This is just another instance in which the patient’s own stem cells were used to help. The patient had nothing to lose (no side effects because they were his own stem cells), and everything to gain. And gain he did with this miracle.

This reminds me of an amazing story in Germany a few years back in which they actually used a man’s back as an incubator and grew him a new jawbone

Click here to read the whole stem cell article

from Don Margolis

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