Tag Archives: Induced pluripotent stem cell

Stem Cells to Reverse Parkinson’s

A team of researchers has now compared the ability of cells derived from different types of human stem cell to reverse disease in a rat model of Parkinson disease and identified a stem cell population that they believe could be clinically relevant.

Parkinson disease results from the progressive loss of a specific subpopulation of nerve cells. Current treatments provide only relief from the symptoms of the disease and cannot reverse the nerve cell loss.

Stem cells are considered by many to be promising candidate sources of cells to reverse nerve cell loss in individuals with Parkinson disease through their ability to
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Clinical Trial Using Stem Cell in Parkinson’s Disease

Parkinson’s Disease – Medical world has struggled in finding permanent cure for this condition that usually affects men over the age of 50 years, but now this maybe changing with the advent of stem cell based research in regenerative medicine. A significant clinical human trial using these technique now seems feasible in the near future.

Stem Cells and its Potential:

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish
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New Genetic Technique Converts Skin Cells into Brain Cells

A research breakthrough has proven that it is possible to reprogram mature cells from human skin directly into brain cells, without passing through the stem cell stage. The unexpectedly simple technique involves activating three genes in the skin cells; genes which are already known to be active in the formation of brain cells at the foetal stage.

The new technique avoids many of the ethical dilemmas that stem cell research has faced.

For the first time, a research group at Lund University in Sweden has succeeded in creating specific types of nerve cells from human skin. By reprogramming connective tissue cells,
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Macular Degeneration: Awesome results from Stem Cells

CHA Bundang Medical Center has become the first in Asia (the second in the world) to confirm that the transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells is effective in treating age-related macular degeneration (AMD) and Stargardt disease (juvenile macular degeneration) without causing dangerous side effects. Hence CHA Bundang Medical Center is now on the fast track to developing the world’s first hESC-based therapeutic product.

A Korean research team, led by Professor Song Won-Kyung from CHA Bundang Medical Center, and CHA Biotech (a leading S. Korea-based biotechnology firm focused on stem cell therapies) jointly issued an
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From Stem Cells to Lung Cells

Bronchi, bronchial tree, and lungs. (Photo credit: Wikipedia)

How do you grow stem cells into lungs? The question has puzzled scientists for years. First you need the right recipe, and it took BU researchers Darrell Kotton, Tyler Longmire, and Laertis Ikonomou seven years of trial and error and painstaking science to come up with it. “A lot had to happen to make a lung,” says Kotton. “It was a little more complicated than Julia Child’s ‘heat, eat, bon appetit.’”

Kotton is a School of Medicine associate professor of medicine and pathology and codirector of the Center for Regenerative Medicine (CReM),
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