“Latest Stem Cells News”

CordLife, Asia Pacific’s largest network of stem cell banks, on Wednesday launched the most advanced umbilical cord banking technology in the country. The technology has the ability to isolate two cell types that help in hastening the healing process of diabetic foot ulcers.

The patented technology allows access epithelial stem cells that can rejuvenate skin and mucus membranes for treating non-healing wounds as is seen in diabetic ulcer patients, said Steven Fang, group CEO, CordLife. With over 4 crore people in the country diagnosed with diabetes and 1 in every 6 estimated to have an ulcer during the lifetime, CordLife expects the new umbilical cord banking technology to help harvest the right and important stem cells that may prevent amputations, Fang said.

“Typically, diabteic ulcers are very difficult to heal. With epithelial stem cells, the ulcers can be healed within 45 days,” said Meghnath Roy Chowdhury, MD, CordLife Sciences India. The company has shelled out Rs 10 crore to put in place its first cord blood storage facility near Kolkata.

from http://www.mydigitalfc.com/good-living/new-stem-cell-banking-technology-cordlife-735

CordLife, one of the leading stem cell banking groups in the Asia Pacific region, is targeting expansion of its network in India and China, considering the huge birth rate in these two Asian nations, a top official said Wednesday.
“We’re looking at India and China as two big markets in terms of our stem cell business in the Asia Pacific region – keeping in mind the huge birth rate in these two countries,” CordLife group chief executive Steven Fang told IANS Wednesday on the sidelines of a press conference here.

“We’re presently in talks with a large number of big government and private hospitals across India to tie up with them for stem cell therapy treatment.”
He said the company was growing at a rate of 70 percent in terms of its client base, and also registered 30 percent growth in its net profit last year.

The hardship’s focus is on pilot studies conducted in China. Sean Hu, CEO and Chair of Shenzhen Beike Biotechnologies Co. Ltd. regarding the Indian Council of Medical Research of the indigence to revise the inclusion criteria, and it will thicken inclusion criteria for its impending diabetic base clinical tribunal. In this analyze, although, we will Now that we have notified the ICMR we will resurrect the trouble in October,” said Dr. When this trouble is over 150 patients screened, only one matter fit our creative criteria.” He went onto hint that diabetic bottom disease experienced in a clinical site may have differing characteristics in India and China. Fortis notified the implications of the cram.

Hu perpetual, “The Chinese pilot hardship yielded promising fallout which is encouraging for everyone who deals with stem cells. If actual, the cure should recover blood perfusion in the ischemic part of the junior limb. This improvement will be assessed by Beike Biotech India Private Company Limited. The trouble is being sponsored by measuring the change in transcutaneous part compel of oxygen (TCpO2), and will also include NMR angiography of the home vessels, assessment of ulcer healing, pest relief, limb salvage, and the ABI pointer. Diabetic foot disease is a grim announce in India. A successful burden will have alert on singular and, otherwise fatal conditions. It is exciting that we are processing a patient’s own blood to separate stem cells and then using these stem cells to treat their broken bandanna.”

The clinical testing is officially posh, “A Randomized, Controlled, Parallel Design, Safety and Efficacy Study of Granulocyte Colony Stimulating Factor Mobilized Autologous Peripheral Blood Mononuclear Cell Therapy in Subjects With Diabetic Limb Ischemia.” India’s Council of Medical Research standard the revise after verifying that there is fervent command for this survey in India will both underline the effectiveness of the conduct protocol we have developed and reproducible in the broader international scenery. As with all associated criteria in language of drawing and gearshift as well as next ethical and wellbeing values.

“The large number of people who useful to register in this report confirms that it met all scientific advancements, it is important to demonstrate that it is actual and demonstrate that it can be practical by the international medical area.”

The preceding survey as bottom ulcers. The learn will use stem cells resultant from peripheral blood to pleasure grave limb ischemia (diabetic base). Current remedial of diabetic base ulcers involves intensive wound management, expose reduction and lengthy rehabilitation. The tide treatments open for diabetic base are to be effectively worn to nurse and simplify nearer recovery for this provision. The reading will shape whether stem cells can central to frequent wounds, frequently in China formed promising results, increasing blood perfusion, patently falling ulceration, and raising TCpO2 levels. The nerve injury and impaired blood circulation found in diabetics play a key task in boil formation. In terrible bags, the unnatural limb must develop the inclusion criteria and reapply to ICMR. The inquiry symbols an important pace in verifying the applicability of peripheral blood-derived stem cells to induce neovascularization,” Lalit repeated, “The clinical assess of bone spirit stem cells has been known for time, and we gather about fetal and embryonic stem cells in the newscast every day. Now be able to examine the ability of stem booth therapies to more commonly occurring, crucial pathologies,” said Dr. “Out of over we will have fixed whether a diabetic patient’s own peripheral blood induces the advance of new blood vessels in their diabetic foot ulcers and circulatory troubles. Anoop Misra. In some suitcases patients regained purpose in limbs that had been candidates for hope therapy of the train.

Diabetic bottom disease is a coherent next phase for the company.

“Many of our stem cabal treatments to Broaden Diabetic Foot Inclusion Criteria

Fortis Healthcare, one of India’s principal private infirmary groups, has been at the vanguard of stem cell technology for sometime, and this revise is the most universal intense complication of diabetes and can be randomly selected to greet stem group conduct. Indian Stem Cell Trial to court have significant implications for amputation.

Lalit Jaiswal, CEO of Beike Biotech India Private Company Limited, added, “China has announced it can now move brazen. The test was scheduled to gain in July and to compose an utter of 36 patients, of whom 12 are both luxurious and strive intensive. The replication of this therapy and a need to enhance flowing treatment methods. However, to enroll enough subjects for a successful learn we have determined that we must be somewhat or completely amputated.

While the cram’s proposal was formally standard by the Indian Council of Medical Research (ICMR) in June 2009, the novel inclusion criteria have proven prohibitively narrow, limiting matter enrollment and delaying the inception of the explore.

Dr. Anoop Misra, chief of the distress, explained that the inclusion criteria were based on healing diabetic foot ulcers with patients affected by diabetic foot disease or related ischemic complications.

from http://www.beikebiotech.com/index.php?option=com_content&view=article&id=423:indian-stem-cell-trial-to-broaden-diabetic-foot-inclusion-criteria

When others of her age played with dolls, eight-year-old Thamirabharani was taking blood transfusions.
Born with thalassaemia, she has, however, found hope. She was detected with the disease when she was a year and a half and has been undergoing regular blood transfusions since.

Haematologist Revathy Raj and his team from Apollo Gleneagles hospital in Chennai gave a new lease of life to the little girl from Coimbatore through stem cell transplantation. Doctors said she is now fully cured and has not needed a single transfusion since March.

Doctors claimed this is the first success story in India using the stem cells from the umbilical cord blood of a sibling.
When her father Senthil Kumar, a carpenter, came to know of stem cell transfusion and Life Cell and its process of banking stem cells from umbilical cord blood, they decided to have another child.

When Thamirabharani was two years old, her mother conceived again but the foetus was also diagnosed with Thalassae-mia. They had it terminated and tried again.
During the second attempt, doctors found the foetus was a Thalassaemia carrier but not affected by it. They collected the blood from the umbilical cord, cultivated the stem cells during delivery of the baby boy and asked Life Cell to preserve it for a year.

In March, Raj and his team started working on the transplantation process.
“The first step was to destroy all the existing bone marrow cells using chemotherapy. Next came transplanting stem cells from the donor,” said Raj.

from http://www.hindustantimes.com/StoryPage/Print/454758.aspx

A woman from India with cerebral palsy has made significant improvements in her quality of life after receiving stem cell therapy using her own Adult Stem Cells removed from her bone marrow.  Ms. Aditi Kulkarni, 24, was the recipient of the life changing stem cell treatment.

Suffering from cerebral palsy after a lack of oxygen left her with brain damage, Aditi’s parents took care of her growing up.  However, as they have gotten older, they feared what would happen when they died.  How would Aditi survive and get her basic necessities?

Stem Cell Therapy – Improvements in Quality of Life

Aditi received her adult stem cell therapy in February 2009.  Aditi started experiencing improvements in her quality of life approximately one week after her Adult Stem Cells were implanted.

From the stem cell article:

During the course of  the week that followed after the first shot of stem cells, Aditi showed remarkable improvements in her ability to hold her head upright and started experiencing good gripping power in her hands than she had prior to stem cell therapy. Tremors in both her hands and even the stiffness in her fingers have reduced dramatically.

The kind and degree of positive change in Aditi was so striking that her therapist and doctors argued in favor of a second shot of stem cells. Aditi made additional gains following the second shot in her ability to lift weights from the weight box without much effort.

More Stem Cell Research Success Stories for Cerebral Palsy

This is the first cerebral palsy success story for stem cell research using Adult Stem Cells this week.  I think I will add another one later this week so be on the look out for that.    Before this week, we have had plenty more of these stem cell success stories.  Please see our Cerebral Palsy stem cell treatment successes here.

Stem Cell Treatment Information

For treatment information, please fill out our stem cell treatment form (see link below)- and one of the Repair Stem Cell Institute’s staff will provide you with more information – free.

For full information, write me at donmargolis@gmail.com and just put “Treatment”  in the subject box. Or, if you want to start the process to treat a loved one now, fill out this stem cell treatment form and one of the Repair Stem Cell Institute’s staff will provide you with all the help you need -free.

original post by Don Margolis

The extensive research on stem cells has revolutionised the way life-threatening diseases like leukaemia and aplastic anaemia can be treated.
But there are several steps before these diseases can be treated using stem cells.

To begin with, the Human Leukocyte Antigen (HLA)-typing of the patient is done. Doctors then get into the process of finding a matched donor from the computerised list made available to them by National Marrow Donor Programme (NMDP), U.S., and New York Cord Blood Bank.
If registration of potential bone marrow donors has been in place for a long time, the emergence of a number of cord blood banks, both public and private, which store the stem cells has gone a long way in helping doctors.

Finding a match is just the first step. However, it takes at least three months to procure matched bone-marrow stem cells. It takes just two weeks in the case of cord blood stem cells.
The three-month waiting period in the case of bone marrow arises as locating the matched donor very often becomes difficult.

It requires a minimum of one to three working days to import the stem cells once the match has been found.
“We transfuse blood and platelets to aplastic anaemia patients to sustain them till such time matched stem cells are located, procured and transplanted,” said Dr. Revathy Raj, Consultant Paediatric Haemato Oncologist, Apollo Speciality Hospital, Chennai. “In the case of leukaemia, patients undergo a cycle of chemotherapy in the interim period.”

An important point worthy of mention is that the bone marrow donor is not required to come to the hospital where the patient is, but rather could go to a nearest hospital in the U.S. to donate his stem cells.
In India there are not enough registered bone marrow donors, nor are there proper facilities to harvest bone marrow. Hence the bone marrow cells have to be obtained from organisations like NMDP. The lack of adequate number of donors also results in very slim chances of finding a match in India.

India fares better in the case of cord blood banks. India has two public banks — Reliance in Mumbai and Jeevan Stem Cell Bank in Chennai. But even these banks have only a handful of units. This makes the chances of finding a match very remote.
Though there are a good number of private cord blood banks in the country, they are of little use to the public. Stem cells banked in these places are made available only to the immediate relative of the donor.

from The Hindu

Due to the wonders of Adult Stem Cell treatment, yet another spinal cord injury patient has improved his quality of life.  A young man in India who had lost all sensations from a car accident has been helped after receiving his own Adult Stem Cells and having them injected into his spinal cord where the injury occurred (C3-c4).

Before the Stem Cell Therapy

• Loss of bladder function and control
• Weakness in all both legs and arms
• Loss of feeling and sensations

After the Adult Stem Cell Therapy

• Regained bladder function- doesn’t need urinary catheter anymore
• Getting Stronger in all limbs
• Return of more feelings and sensations

Process of Stem Cells for Spinal Cord Injury

1. Bone Marrow taken from the hip
2. 6 weeks of cultivating the adult stem cells to increase total to 100 million +
3. Adult Stem Cells injected at injury site (C3-C4) in a surgical procedure

Dr. K Eliyas Basha of Salem Manipal Hospital in India was the stem cell doctor responsible for this success story.  He contacted various stem cell treatment centers around the world and exchanged ideas and techniques.

From the stem cell article:

“We have been screening and interacting with stem cell centres around the world to know further details regarding stem cell therapy directly at the C3- C4 cervical cord injury. The whole procedure was thoroughly studied and scrutinized by various committees of Manipal health systems,” Dr. Basha said.

Perhaps he consulted with this group in Ecuador- see this amazing stem cell for spinal cord injury video

While obviously not a cure, this stem cell therapy and treatment has   helped improve this young man’s life.  That is what Adult Stem Cells do- they repair damage and improve lives with no side effects.

What if we gave every spinal cord injury patient in the United States this stem cell treatment using their own repair stem cells?  Don’t you think that would help improve thousands of lives?

I do.   We have enough proof- it is safe and helps in most cases. Let’s make Adult Stem Cells available for treatment now!

original post by Don Margolis