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A biodegradable tissue to repair hearts after a heart attacks or to cure congenital malformations. A tissue that acts like a porous, accordion-like medium onto which cardiac stem cells are ‘implanted’ has been created by scientists from the prestigious Massachusetts Institute of Technology in Boston (MIT). This “bioscaffolding” integrates perfectly with cardiac tissue and creates a biological “band-aid” that is slowly reabsorbed and repairs cardiac muscle.
Compared to similar previous attempts, explained George Engelmayr in “Nature Materials” magazine, the advantage of the “bioscaffolding” is that it faithfully mirrors cardiac tissue structurally and mechanically, and
What are mesenchymal stem cells? where are they found in the human body? What are their most promising clinical applications? Gordana Vunjak-Novakovic of Columbia University gives us an answer to these questions and and an outlook on the future of mesenchymal stem cells.
Scientists have for the first time grown embryos that contain a combination of pig and human stem cells, in a step toward one day growing transplantable organs, a study said on Thursday.
However, the research remains at a very early stage and proved more difficult than expected, the researchers reported in the peer-reviewed journal Cell.
“This is an important first step,” said lead investigator Juan Carlos Izpisua Belmonte, a professor in the Salk Institute of Biological Studies’ Gene Expression Laboratory.
“The ultimate goal is to grow functional and transplantable tissue or organs, but we are far away from that.”
Scientists implanted adult human
Like Samson, researchers in the field of stem cells have used the jawbone to make a point. Dr. Gordana Vunjak-Novakovic and her team at Columbia University have manipulated adult stem cells to grow one of the most difficult sections of bone to replace, the temporomandibular joint. This jawbone was created by allowing pluripotent cells harvested from marrow to grow in a scaffold that was fashioned to mimic the TMJ’s shape.
It is the first accurate and anatomically sized bone created by stem cells in a lab. Dr. Vunjak-Novakovic hopes that this new creation will serve as a proof of concept
A recent report published in the medical journal Stem Cell Reports, sheds light on breakthrough research regarding the use of thyroid cells derived from stem cells for new therapies. Scientists at Boston University’s School Medicine led the work.
They have pinpointed a means of efficiently engineering thyroid cells by way of stem cells that will eventually help analyze and treat thyroid diseases (…)
The breakthrough described above was discovered after studies were performed on mice. Stem cells are valued as they can mature into an array of different cell types.