Italy is the top country in the world for hematopoietic stem cell transplants per million inhabitants, said Alessandro Nanni Costa, the director of the National Transplant Center (CNT), presenting data today in Rome from a study by the Welfare Minister on umbilical cord stem cells.
Italy boasts a registry of 370,000 healthy adults available to donate blood stem cells.
The units of umbilical cord blood preserved in Italian biobanks number 17,503, while in 2008, only 141 were used in Italy or abroad.
The objective is to reach 80,000-90,000 units of umbilical cords preserved from which blood stem cells can be removed
Gerhard Bauer, an American researcher and expert on ‘mother’ stem cells, during the 50th congress of the American Society of Hematology (ASH) in San Francisco, announced that human testing for an AIDS treatment based on genetically modified stem cells could begin within 5 years. Bauer has been working for the past 10 years on modified stem cells that could repair strongly compromised immune systems in HIV patients. “For this reason the apparent success obtained by German researchers on an American patient with AIDS and leukemia reinforces the idea that we are on the right path.”
Last month the German
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Not all stem cells are ‘good’ at aiding the heart in repairing itself after a heart attack. Apparently, ‘baby cells’ present in human fat are the best equipped to perform this task and could be used in human testing by the end of 2009. “ We have seen that a simple stem cell transplant into a heart after a heart-attack is not sufficient. There are different types of stem cells that are better adapted to aiding the heart in the healing process. Instead of hematopoietic stem cells used in initial studies, mesenchymal
Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery. In a paper published online this week in Nature, researchers at the University of California, San Diego School of Medicine elaborate upon a crucial signaling pathway and the role of key proteins, which may help clear the way to generate HSCs from human pluripotent precursors, similar to advances with other kinds of tissue stem cells.
Principal investigator David Traver, PhD, professor in the Department of Cellular and Molecular Medicine, and colleagues focused on the
Gerhard Bauer & Jan A. Nolta
A new experimental technique in the future will remove skin cells from HIV patients, manipulate the cells bringing them to a state similar to that of stem cells, and then re-implant them in the same patient to eliminate the virus. The technique is still in the experimental phase in mice, but according to Gerhard Bauer, presenting the initial results of his study today at the 50th American Society of Hematology Congress in San Francisco, it’s a possibility. Bauer has been working for more than 10 years on this technique together with