Tag Archives: Hematopoietic stem cell transplantation

Stem cell donor saves thalassemic boy

A two-year-old Delhi boy suffering from thalassemia got a new lease of life after a Bangalorean donated his blood stem cells to him. This is the first reported case in India of a thalassemia patient receiving blood stem cells from an unrelated donor.

Garvit Goel was advised to go for a blood stem cell transplant a year ago. None of his family members qualified to be potential donors. That’s when Sumeet Mahjan, a software professional from MindTree, stepped in.

For Sumeet, the turning point came in 2011 when his colleague’s 11-year-old son was diagnosed with leukemia. MindTree requested Datri, an NGO
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New Stem Cells Technique Offers Hope for Kids With Immune Deficiency

For children born with immunodeficiencies, researchers may have found a better way for them to get the help they need from stem-cell transplants (…)

Children with primary immunodeficiencies have genetic defects in their immune system that leave them open to infection and other complications. Stem-cell transplants can replace the defective immune system with one derived from healthy donor bone marrow, but without a stem-cell transplant, many of these children might die, the researchers noted in a journal news release.

In order to create space for the donor stem cells and prevent rejection, the patient usually undergoes chemotherapy, radiotherapy or both. This
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Stem cells: bone marrow transplants (BMT)

Early September 2016, on a late evening I received a call from the E.R (Emergency Room) that a young 18 year old boy’s family was seeking an emergency opinion from a hematologist for their son.

He was found to have severe pancytopenia [severe reduction of all three cell lines –Hemoglobin (Hb), white blood cells (WBCs) and platelets] noted on a blood count (CBC) done for progressive fatigue over a month, and new onset rashes all over his body since a day.

His evaluation revealed a related rare disorder of the bone marrow, called severe aplastic anemia (SAA), that occurs due to
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Indian doctors cure thalassaemia using stem cells

When others of her age played with dolls, eight-year-old Thamirabharani was taking blood transfusions.
Born with thalassaemia, she has, however, found hope. She was detected with the disease when she was a year and a half and has been undergoing regular blood transfusions since.

Haematologist Revathy Raj and his team from Apollo Gleneagles hospital in Chennai gave a new lease of life to the little girl from Coimbatore through stem cell transplantation. Doctors said she is now fully cured and has not needed a single transfusion since March.

Doctors claimed this is the first success story in India using the stem cells
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Stem Cell Therapy without Stem Cell Transplants

Transplantation of hematopoietic stem cells has been widely used as an approved treatment of leukemia, lymphoma and certain autoimmune conditions for the past fifty years. Other adult stem cells have demonstrated safety and efficacy in pre-clinical research and clinical trials. Mesenchymal stem cell transplants have been most widely studied in animals, especially horses & dogs, and humans. Many of these studies have focused on skeletal-muscular effects.

There is significant support for safety and efficacy in osteoarthritis, including cartilage regeneration, pain and inflammation reduction as well as recovery of function using intra-articular MSC injections. There are fewer studies of neural stem
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