Tag Archives: Hematopoietic stem cell transplantation

Understanding Stem Cells

“For centuries, scientists have known that certain animals can regenerate missing parts of their bodies. Humans actually share this ability with animals like the starfish and the newt. Although we can’t replace a missing leg or a finger, our bodies are constantly regenerating blood, skin, and other tissues.

The identity of the powerful cells that allow us to regenerate some tissues was first revealed when experiments with bone marrow in the 1950s established the existence of stem cells in our bodies and led to the development of bone marrow transplantation, a therapy now widely used in medicine.

This discovery raised
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New Stem Cells Therapy Treating Crohn’s Disease

Cellular therapy with stem cells is revolutionizing the focus of treatment of many serious diseases. Replacing the cells of damaged tissue with other new cells from the same patient is already a reality. This is the basis of cellular therapy and regenerative medicine, the latest great advance in biomedicine.

In this line, Hospital Clínic, Barcelona is exploring an innovative cellular therapy that uses stem cells to treat Crohn’s disease, a chronic genetic disease that affects 1% of the population in Spain and which has considerable impact on the quality of life of the patients. The procedure is based
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Berlin, Germany – Stem cell transplant cures HIV in patient

Stem cell transplantation in a 42-year-old HIV patient with leukemia has wiped out the virus from his body, the doctor of Berlin Charité Hospital confirms.
“The patient is fine,” said Dr. Gero Hutter, a haematologist at the Berlin Charité Hospital. “Today, two years after his transplantation, he is still without any signs of HIV disease and without antiretroviral medication.”

The doctor observed that using the stem cells from a donor who carries a unique gene mutation i.e. delta 32 ccr5 along with a tissue match, could now cure the patient from the HIV virus. Delta 32 ccr5 makes the cells resistant
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Boy whose skin can’t attach is healing

http://mediamill.cla.umn.edu/mediamill/download.php?file=13798.flv#/U_of_M_Sets_Course_For_Cure_of_Fatal_Childhood_Skin_Disease___Academic_Health_Center__University_of_Minnesota_download.php.flv

Physicians at the University of Minnesota and University of Minnesota Children’s Hospital, Fairview have set the path to a cure for a young boy’s fatal genetic skin disease, recessive dystrophic epidermolysis bullosa (RDEB), by using a cord blood and bone marrow transplant. Nate Liao, a 25-month-old from Clarksburg, N.J., underwent the experimental therapy in October 2007.

“We have established a new standard of care for these EB patients, beginning with Nate,” said John Wagner, M.D., the lead University of Minnesota Medical School physician who developed the clinical trial. “Nate’s quality of life is forever changed.”

Because they lack collagen type VII,
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A miraculous Stem Cell transplant

A breakthrough was achieved recently in the case of an 18 year old boy, a case of advanced stage of Aplastic anemia where stem cells of not one but three donors were used to treat him. This spectacular feat was achieved by the doctors at The Netaji Subhash Chandra Bose Cancer Research Institute (NSCBCRI) Kolkata.

18 year old Aman, student of class 12, fainted in school. He was diagnosed for Aplastic Anemia, a disorder where the bone marrow stops producing red blood cells and platelets. He was treated in many hospitals, but no amount of blood transfusions or ‘immuno-suppressant’ medication
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