“Latest Stem Cells News”

Recent stem cell research studies using Adult Stem Cells to treat heart diseases such as congestive heart failure and heart attacks have made the news recently.  And on the surface, these adult stem cell success stories of heart attack victims making amazing recoveries in these research clinical trials is wonderful news indeed.

New Research Trials for Heart Attack Victims

For example, at the Texas Heart Institute, John Hartman who had suffered a heart attack recently had his own stem cells implanted into his heart muscle in a new stem cell research trial.

From the stem cell article:

Dr. Jim Willerson President, Texas Heart Institute, said, “We think the improvement we see is largely from the blood flow increase salvaging the cells that are reversibly injured, allowing them to function normally.”

“That reflects in the patient being able to do better, walk further, breathe better,” said Dr. Emerson Perin St Luke’s, THI Cardiologist.

Stem Cell Trial for Congestive Heart Failure

Also, in another stem cell research trial at Vanderbilt, an unnamed 65 year old congestive heart failure patient was treated using his own Adult Stem Cells again.   Dr. David Zhao, director of the cath lab there said “The patients who stand to benefit from this approach include those whose coronary arteries are so diseased that nothing else could be done,”

What About Heart Disease Patients Who Can’t Get Adult Stem Cells?

However, the headlines don’t mention the millions who are suffering and dying after having heart attacks (1.25 million per year in the United States) and are in congestive heart failure and don’t have the opportunity to receive adult stem cell treatment because the FDA has classified a patient’s own stem cells as a drug- thus slowing down progress and starving heart patients of a “drug” with no side effects or ethical issues and only has upside.

For every Barry Brown or Kenneth Milles, heart attack victims who were lucky enough to get into a US stem cell research clinical trial using their own stem cells, there are millions of heart disease patients who do not have that opportunity. And for that, we have the FDA to blame.

And that is only addressing adult stem cell therapy for heart disease………what about the hundreds of other conditions that can be helped or improved by Adult Stem Cells?

Sad.

For more information on clinical research trials in the United States, go to the Clinical Trials website – www.clinicaltrials.gov

As part of a new stem cell treatment series, I am trying to find patients who have been helped by Adult Stem Cell research and therapy.  In May, I featured a Multiple Sclerosis patient named Arndt Roehlig who described his successful  stem cell experience in Israel in his own words.

Barry Brown- Stem Cell Study Volunteer

This time, I present Barry Brown, a heart attack victim who was involved in a stem cell research study at the University of Miami.  We had presented Barry before back in May in this stem cell post .  Barry was kind enough to write to me and wished to present his own stem cell success story in his own words.

A Stem Cell Success Story

Hey Don,  Barry here,  sorry its taken so long for me to do this but here goes.

Last February,  after moving from Las Vegas to Miami upon retiring from 20 years in the Air Force, I started getting a dry cough which upon doing some research on my own was attributed to the use of lisinopril.   My cough cleared up but I realized when i would start exerting during exercise I would get a hot flash down the middle of my shoulder blades I would just shrug it off thinking it was just the side effects of the BP drug. A few weeeks went by and I got a cold and I started coughing so much I coughed my chest sore and couldn’t breathe.  After about 10 days of suffering with this I finally went to the doctor.   An Ekg was conducted and the results came back Abnormal.  I’m like ok, Ive been exercising eating well, no caffiene, no Nicotine ( I had Dipped tobacco on and off for 20 yrs) I had just stopped in February.  So I thought  “whats going on?”

Heart Attack Misdiagnosed

The first diagnosis was I was out of shape and needed to lose about 10 lbs. Hmmmm ok ill buy that i need to lose a few lbs, but mind you, just 2  months before that, I was working out 5 days a week doing cardio 45 min a day and weights 3 times a week and teaching 2 circuit training classes so why had my cardiovascular health gone down so quick?? “Im not buying it Doc, run some more tests I want to get back to where i was 2 months ago and I want to make sure 1000% that my heart is healthy to exercise!”

Next test was an echocardiogram that showed some weakening of the lower part of my heart. The  2nd diagnosis was I  need to lose a few lbs and lets see how you are in a month…..”

I thought to myself ” how am I going to lose any weight?  first off if  I cant walk 15 minutes without feeling like i got 1000 slaps on the back for a good game????”

Watching Hugh Laurie and House Saves Barry’s Life

OK look Doc i said,  “Im no bleeping doctor, but Ive watched enough ER episodes and House to know you can run some dye thru my veins and check my arteries and valves.  I dont know what its called but thats what i want!!!!”

Thallium stress test was what i had done, I stayed on the treadmill about 4 min before I had to get off, the nurse said stay here we want to read the results……. the results were read and off to the 7th floor I went to meet with the Cardiac folks

I met with the Cardiologist he explained to me that they thought there was a blockage in my heart but they want to run a cath up my leg and angioplasty the blockage and put a stent in and that it should take no longer thatn 30 min. He said when can you come back mind you it had been about 2 months since it all first started so i said TOMORROW!!!!!!!!!!!!!!

The day of the Cardiac cath comes, I get on the table and I’m on the table for what seemed like an eternity. The doctor  comes in and says “Mr. Brown we have a few things we need to discuss with you,  some options for you.  Did you know you’ve already had a heart attack?  Fighting back some tears and trying to regain some composure from the lil self deprecation and a little self pity that went through  my mind for a few minutes then a conscious decision made I wasn’t going to let this situation get the best of me. “Ok Doc what are the options???”

The options were laid out…..

1. Option 1 was have a triple bypass get it over with and start living the life I was living just 12 months earlier.
2. Option 2 enter into this radical new study involving stem cell therapy, help open the doors for new research and possibly ways were we can change the lives of others from now on. Where at the time of your surgery you may be injected with your own stem cells at several different areas on your heart with the hopes of healing some of the damaged tissue from your heart attack.  Hmmm that sounded interesting……

As I waited to hear option 3 which was I’m sure going to be take this pill go home and come back in a month you should be fine– it never came I was stuck with two options I guess……

So to me it was a no brainier-  enter into this study have the opportunity to be the FIRST devilishly handsome charming semi fit veteran to have this procedure done and open the doors for other to follow. PERFECT….. There pains and trails, as well as numerous sleepless nights that I had to endure of course this is real life, there was a point in Aug where tests had shown I had an enlarged prostrate so I needed to have to have a biopsy done to be cleared of cancer so  I could remain in the study. So, there I was thinking to myself wow I have Heart disease and prostrate cancer. I needed to be cancer free because if I had cancer when injected with the Stem cells it could move to the cancer and make it spread faster.

SO after a bunch more tests to get me back into the study since it had been over three months for all the initial work I was finally cleared back in…..

Then finally the date, Nov 20 2008 triple bypass day….. I’m lobbing congress to have that a legal holiday so you’ll have Veterans Day, Barry’s Bypass day and Thanksgiving all in Nov…

The 3 days I spent, no 4 days I spent in the hospital were a blur and that is where I made my mind up that I was going to get back on my feet and get busy getting healthy again. And it started with one of my post op meals ribeye steak and French fries……. Ok so the dietician was off the week I was in ICU no biggie….. Ill just get something else off the MENU…..

Of course anyone who has stayed in a Hospital knows you don’t get any rest in the hospital,  it really started with my release from the Hospital and qtr mile walks after 7 days,  to half mile walks after 2 weeks and pretty much adding mileage up to 3 miles in February when I started walking with a 30 lb pack 3 times a week. I’ve had days where my chest hurt so bad I didn’t want to do it but I pushed myself to do it so I could start strengthening my heart and get better so my quality of life would improve.

It has been a long road its been a challenge but with the great help of the Miami VA and the University of Miami Doctors and staff and the support of friends and family my outlook hasn’t looked better, From last summers 3 clogged arteries and not being able to walk a qtr mile, to my own fitness training and life expectancy its all good.

Its been pretty much a whirlwind the last week I was asked to be at the dedication of a new Stem cell research lab located with in the school of Medicine at UM and I did a TV interview the other day and word on the street  is that Mens Health wants to interview me also so more to come on that. Also with the help of one of my marketing friends Glen Werstler in Ohio and his marketing group at page gravy had started me out with my own web page and Non profit organization called One Heart to start foundation. I’m excited to try to get people more aware about this medical breakthrough. thanks for taking your time and reading.

Sincerely

Barry

The song “Take another little piece of my heart” by Janis Joplin has new meaning today as doctors in Los Angeles have taken Adult Stem Cells directly from a heart attack patient’s heart and used those stem cells to treat the patient in an adult stem cell research study.

As part of a Phase 1 clinical research study, Dr. Eduardo Marban, of Ceders Sinai Hospital, did a minimally invasive biopsy and took a piece of Kenneth Milles heart muscle after Kenneth had suffered a heart attack.

The piece of his heart was sent to a lab where the Adult Stem Cells were cultivated to produce millions of Kenneth’s heart stem cells. 4 weeks later, the stem cells were implanted back into Kenneth’s heart muscle. The goal to help regenerate the damaged heart tissue from the heart attack.

From the stem cell article:

“We seek to actually reverse the injury that has been caused by the heart attack, by re-growing new heart muscle to at least partially replace the scar that’s formed,” says Dr. Eduardo Marban of Cedars-Sinai Heart Institute.

Doctors are using stem cells, the body’s master cells, because they can transform into different kinds of tissue.

Marban says, “These cells that we’re putting in come from the heart itself, and are predestined to generate heart muscle and blood vessels.”

Other types of stem cells, like bone marrow, have been studied for heart repair, but with mixed results. Animal studies indicate heart stem cells do a better job. The problem is: the heart has so few stem cells that researchers have to grow more.

And they did grow more- doesn’t seem like that big a problem.   Hopefully the money for this problem came from the California taxpayers- at least that would be the first positive that ever came out of their stem cell funding- using heart stem cells to help people.  However, the cynic in me says that is not the case.  I’m guessing it was privately funded.

Kenneth was the first patient treated with this method and the results are not in yet.  However, why wouldn’t it work? The patient’s own Adult Stem Cells are used.  The patient has nothing to lose.

Another congestive heart failure patient has been helped by stem cell research using adult stem cells. Terry Areford, 62, a multiple heart attack victim has been given a 2nd chance at life after receiving Vescell stem cell treatment to heal his heart muscle in Thailand.

Congestive Heart Failure Symptoms

Terry was dying. He was slowing down. He had the usual symptoms of congestive heart failure. He had shortness of breath. He could barely walk 50 feet slowly. However, Terry still had hope. His daughter came across the Vescell website and contacted them.

Adult Stem Cells From Your Own Blood

For those of you unfamiliar with Vescell stem cell therapy in Thailand, it is a process created by a company called Theravitae in which adult stem cells are removed from the patient’s blood (similar to a blood donation) and then multiplied into a therapeutic dose and then implanted into the patient’s heart muscle and/or coronary arteries.

But back to Terry’s stem cell story-

Before Vescell Treatment

• Ejection Fraction 10%
• Could barely walk
• Severe shortness of breath

After Adult Stem Cells Implanted

• Ejection Fraction at 45%
• Plays 3 rounds of golf per week
• No shortness of breath- outside chopping firewood

3 full 18 hole rounds of golf per week? No kidding Terry?  I am very happy for you.   Like many of the Vescell heart patients recently, Terry has become an adult stem cell advocate and wants other congestive heart failure patients to know that there is still hope out there.

You are welcome to call or email Terry  at 304-594-9377 or his email is bkareford@msn.com

Stem Cell Research in Thailand

This is the third stem cell research success story to come out of Thailand in the last month. See stories from heart attack victims and heart failure patients James Eilert and Andy Jordan as well.   Is anyone in the FDA paying attention to this?  Adult Stem Cells can be used now to help these heart patients with no side effects!  Why do they have to leave the United States for it?

James Eilert went on a 20-mile bike ride the other day! Why is that amazing?

Because18 months ago, the thought of getting on a bicycle was too much exertion for the Michigan native. In 2006, at the young age of 34, James suffered a major heart attack, which damaged his heart muscle.

The heart damage left James fatigued, exhausted and short of breath. It was increasingly difficult to meet the demands of his job as an automotive engineer. He was gasping for breath and sweating all the time. His ejection fraction (EF) had sunk to 20-25%. Feeling depressed, James had given up hope of ever improving his quality of life. However, hope was restored when James found Vescell ™ adult stem cell therapy on the internet.

“I was in Class III congestive heart failure and had given up, but the amount of research and patient success stories I found on Vescell™ gave me new hope. I contacted them immediately,” James said.

On November 14, 2007, James flew to Bangkok, Thailand and received 41 million of his own stem cells via catheter to heal his ailing heart muscle. James exclaimed, “I didn’t feel a thing, it was just a simple catheterization!”

James raved about his experience and the care he received in Bangkok, “I have never been so well cared for in all my years going in and out of multiple hospitals for congestive heart failure. The doctors really listened to me and gave me confidence that they were my partners in improving my heart.”

After the treatment, James was thrilled with the results of the Vescell ™. “I had an echocardiogram only 2 weeks after my stem cell therapy and my completely dead apex was beating again. I was shocked and ecstatic at the same time.”

Since then, James has continued to improve and 18 months after treatment, he says, “I can do anything, the sky is the limit. I am now in Class I heart failure. My ejection fraction is at 50% and my doctors have lifted all restrictions.”

Today, James devotes his spare time to help other patients, as a patient volunteer, “I shudder to think how my life would have turned out if I hadn’t found the Vescell website. I was lucky. I want others to get the same second chance that I had.”

James is one of more than 500 patients who have had the Vescell ™ treatment. VesCell™ harnesses and enhances stem cells’ unique abilities, enabling the patient’s own body to heal itself.

from TransWorldNews

In a stem cell research study at the University of Miami, Barry Brown has had his heart attack healed after receiving therapy using his own Adult Stem Cells. An unlikely candidate for heart disease, Barry was a 38 year old physical trainer in the Air Force when he had his heart attack.

Stem Cell Treatment in Addition to a Bypass Surgery

While receiving treatment at the VA hospital, Brown was approached by Dr. Juan Pablo Zambrano, a cardiologist at the University of Miami who have been conducting a clinical trial in which the heart disease patient is injected with their own Adult Stem Cells just after the completion of bypass surgery. In other words, while the chest is open, it is convenient for the heart surgeon to inject the stem cells into the heart muscle.

Process of Stem Cells for Heart Disease

Barry was accepted into the study and had some of his bone marrow extracted 4 weeks before his bypass surgery was scheduled. The Adult Stem Cells from his bone marrow were isolated and then cultivated so there was enough stem cells to help in the treatment. Then, after 4 weeks the stem cells were injected into the heart at the same time as Barry’s bypass surgery.

And how did it turn out? From the stem cell article:

Things have slowed down for Brown since those hectic first weeks at the VA, but things are speeding up in a different way now. Each week, he has been able to add a quarter-mile to his daily workout walk.

By spring he was up to three miles a day. Now, at 39, he is training to compete in a mini-triathlon.

”And I’m feeling no discomfort,” he said.

Although the initial case studies have been successful, the three doctors know they are facing an uphill battle. They have secured only 11 of the targeted 45 willing participants. Many who have heart damage are unwilling to wait a month for their stem cells to incubate without a guarantee that they will be in the treatment group.

”We are working with the FDA to try to guarantee that those who are in the placebo group do eventually get administered the treatment,” Hare said.

Working With the FDA? Waiting for the Cubs to Win the World Series Too?

In other words, Dr. Hare, who is conducting the study and is playing by the FDA rules, wants to give stem cells to the patients who received the placebo in his study -AFTER the study is completed. Why it would take more than 1 phone call to the FDA to guarantee that those in the placebo group receive the stem cell treatment (after the research is completed!)  is beyond my comprehension.  Not many have accused the FDA of having common sense and compassion.

Sarcasm aside, I am very happy that Dr. Hare is conducting the research study and helping heart disease patients improve their lives with the use of their own stem cells as treatment. Keep on going my friend.