Tag Archives: Harvard Medical School

Stem Cells with potential to become eggs found in ovaries

Researchers found stem cells in the ovaries of young women that have the potential to become healthy eggs. Applications of this discovery may help women have children that were once too old to or left infertile because of disease.

Natalie Melgar-Fetzer, a junior in ICS from Maryland said “It’s interesting because it can give women with reproductive problems the opportunity to have children. So many people want to have babies but can’t for whatever reason.”

Researchers have already created potentially viable eggs from these stem cells by adding a protein to them as well as a gene that makes jellyfish glow
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Stem Cells Used to Grow Hearts

From left to right: A normal pig heart, a pig heart after being decellularised, the pig heart prepared for recellularisation. Photos courtesy of the University of Minnesota.

In a medical first, University researchers have created a beating heart in the laboratory. Using detergents, they stripped away the cells from rat hearts until only the nonliving matrix, or “skeleton,” was left; they then repopulated the matrix with fresh heart cells.

If perfected, the technique may be used someday to generate new hearts for patients. In the United States alone, about 5 million people live with heart failure, 550,000 new cases are
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Birth of new cardiac cells

A sophisticated imaging system, multi-isotope imaging mass spectrometry (MIMS), demonstrates cell division in the adult mammalian heart. Researchers were surprised to find that new heart muscle cells primarily arose from existing heart muscle cells, rather than stem cells.

Recent research has shown that there are new cells that develop in the heart, but how these cardiac cells are born and how frequently they are generated remains unclear.

In a study from Harvard-affiliated Brigham and Women’s Hospital (BWH), researchers used a novel method to identify the new heart cells and describe their origins.

The research was published today in Nature.

“The question about how
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Enhancing the regenerative capacity of stem cells

tem cell scientists scored what at first appeared an easy win for regenerative medicine when they discovered mesenchymal stem cells several decades ago. These cells, found in bone marrow, can give rise to fat, bone, and muscle tissue, and have been used in hundreds of clinical trials for tissue repair. Unfortunately, the results of these trials have been underwhelming. One problem is that these stem cells don’t stick around in the body long enough to benefit patients.

But Harvard Stem Cell Institute (HSCI) scientists at Boston Children’s Hospital aren’t ready to give up. A research team led by Juan Melero-Martin
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Stem Cell Therapy is Reality

The mesenchymal stem cells found in the bone marrow can give rise to bone, fat, and muscle tissue, and have been used in hundreds of clinical trials for tissue repair.

Unfortunately, the results of these trials have been underwhelming, the main problem being that these stem cells do not stick around in the body long enough to benefit the patient.

Researchers have now found that transplanting mesenchymal stem cells along with blood vessel-forming cells naturally found in circulation improves results.