An international team of physicians and scientists in Florida have discovered a way to treat cardiomyopathy (heart disease) with adult stem cells, including a rare metabolic condition otherwise requiring heart transplant.
Regenocyte Therapeutic is using stem cells extracted from patients’ blood to repair damaged heart muscle, regenerate tissue, and create new vessels to improve circulation. According to the organization’s director of Cardiology and Vascular Disease, Zannos G. Grekos, M.D., by applying specific growth factors to the patient’s stem cells the team creates a new cell population which is educated to target the area of damage or deficiency when placed into
A group of British doctors are preparing for human clinical trials that will take a person’s bone marrow stem cells, transform them into heart stem cells and inject them into the heart, where they can go to work repairing damage.
“Placing heart stem cells into the heart to repair has a very good chance of working; because the stem cells are the patient’s own there are no problems with rejection,” said Professor Sian Harding, of Imperial College London.
The British researchers plan to use a technique that was pioneered at the Mayo Clinic. They will remove 40 milliliters of bone marrow
Revolutionary as they may be, stem cells cannot escape the need for food. And until now, that food has represented a costly part of developing stem cells.
But that is about to change. The East Greenbush-based Neural Stem Cell Institute has developed a new substance that will substantially lower development costs.
“Stem cells are unstable,” as Christopher Fasano, the Institute’s director of research and development, says. He explains that they need a constant supply of food and a substance called a “growth factor,” or they start developing into different types of body tissues on their own, and cease being useful to
MIT engineers have boosted stem cells’ ability to regenerate vascular tissue (such as blood vessels) by equipping them with genes that produce extra growth factors (naturally occurring compounds that stimulate tissue growth). In a study in mice, the researchers found that the stem cells successfully generated blood vessels near the site of an injury, allowing damaged tissue to survive.
Why it matters: Stem cells hold great potential as a way to promote tissue regeneration. However, this approach has been limited because stem cells don’t produce enough growth factors after transplantation. The researchers’ new super-charged stem cells could be used to
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In the near future, hearts that have just suffered a heart attack will be able to repair themselves, according to an incredible discovery of how to reeducate cardiac stem cells to repair damaged hearts. In fact, stem cells normally perform the delicate task of repairing cardiac muscle, but after a heart attack the cells no longer carry out this highly important self-repair.
Italian scholars at the ‘Sapienza’ University in Rome and the European Molecular Biology Laboratory (EMBL) in Monterotondo, have discovered why these cells stop functioning correctly, and now understand how to induce them to