Stem cells from the ovaries of reproductive age women can give rise to cells that appear to be mature oocytes, suggesting that women can produce more eggs than the batch they are born with. The findings, reported in the March 2012 issue of Nature Medicine, open the door to a new generation of assisted fertility treatments.
Germline stem cells that produce oocytes in vitro and fertilization-competent eggs in vivo have been identified in and isolated from adult mouse ovaries. Here we describe and validate a fluorescence-activated cell sorting-based protocol that can be used with adult mouse ovaries and human ovarian
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An extremely valuable source of eggs has been discovered in female mice. The discovery was described as a potentially infinite source of female fertility, or germline stem cells, which can continue producing new egg cells in adults, which could be a cure for sterility and menopause.
The discovery was made by Ji Wu of the University of Shanghai Jiao Tong and contradicts previous research on the female reproductive system, possibly paving the way for new prospects to treat sterility and revolutionize female reproduction, which after menopause could make use of germline stem cells that were previously isolated