Tag Archives: Genetic engineering

NSF award to stem cells engineering

From a simple blood draw, Krishanu Saha, a researcher in WID’s BIONATES research group and assistant professor of biomedical engineering, could enable doctors to create stem cells to develop drugs personalized to their patients.

As part of his $400,000 National Science Foundation CAREER Award over the next five years, Saha will focus on improving the process to directly evolve DNA sequences and proteins in human stem cells.

Stem cells have the potential to develop into many different cell types, which makes them ideal for a variety of medical research projects.

The evolution of synthetic DNA sequences in human stem cells could catalyze
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In muscle stem cells age matters

Image by foundphotoslj via Flickr

CHICAGO (Reuters) – A new understanding of the genes that make muscle cells may change the way researchers think about stem cell transplants for muscular dystrophy and muscle injuries, U.S. researchers said on Wednesday.

In a surprise finding, they said genes important for forming muscle cells in embryos and newborns are not normally active in adult stem cells.
And researchers hoping to use muscle stem cells in stem-cell transplant therapies should not assume genes that control early muscle development serve the same purpose in repairing adult muscle, Christoph Lepper and colleagues at the Carnegie Institution in Baltimore
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Face-surgery patients to grow their own bones

BRITISH face surgeons are to grow new skull, cheek and jaw bones on patients’ backs using their own stem cells.
The surgeons, from Barts and the London NHS Trust, hope to use the technique to help people whose facial bones have been destroyed by cancer or injury.

Four patients are awaiting the treatment, which the surgeons believe could eventually become a less risky alternative to face transplants. Two are cancer victims and two have had accidents.
The team, led by Iain Hutchison, will make the first attempt to grow replacement bone from a patient’s own stem cells in Britain.

The procedure involves constructing
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CRISPR: Genetic Engineering Will Change Everything Forever

Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly.

Imagine you were alive back in the
nineteen eighties and were told the
computers would soon take over
everything from shopping to dating and
the stock market the billions of people
would be connected via kind of web that
she would own a handheld device orders
of magnitude more powerful than
supercomputers it would seem absurd but
then all of it habit science fiction
became our reality that we don’t even
think about it
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UCLA-engineered stem cells seek out and kill HIV in living organisms

Expanding on previous research providing proof-of-principle that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers has now demonstrated that these cells can actually attack HIV-infected cells in a living organism.

The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal model, said lead investigator Scott G. Kitchen, an assistant professor of medicine in the division of hematology and oncology at the David Geffen School of
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