Tag Archives: Genetic disorder

Stem Cells used to Grow Bone in Boy’s Jowl

Cincinnati Children’s Hospital Medical Center, known for “miracle” surgeries, has completed a medically historic procedure where doctors used stem cells taken from the fat tissue of a 14-year-old boy and combined them with growth protein and donor tissue to grow viable cheek bones in the teen.

Brad Guilkey, 15, suffers from a rare kind of genetic disorder known as Treacher Collins Syndrome, where the bones and other tissues are prevented to develop in the face (…)

The medical team implanted cadaver bone into Brad’s face in May, and then they injected his own stem cells into the donor bone to fill
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Stem cell-gene therapy technique cures genetic disease in human cell line

Image by JohnnyRokkit via Flickr

Scientists are one step closer to creating a gene therapy/stem cell combination to combat genetic diseases. With work, this research may lead to not only curing the disease, but also repairing the damage left behind.

While gene therapy is a burgeoning field that has shown great results in treating genetic disorders, many of those diseases leave behind heavily damaged tissue that the body is unable to repair. So even if the disease is completely eradicated, quality of life may not necessarily improve, and without help, health can still continue to deteriorate.

Since stem cell research began, there
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Woman returns from China after stem cell surgery

A young woman is back home after a desperate journey to China for experimental stem cell treatment to heal her brain.

It wasn’t a disease or a genetic defect that led to her condition. Instead, Jackie Murphree, 22, went into a coma and woke up unresponsive and in need of wheelchair after a drunk driver struck her car.
The Decatur High honor student turned Aggie was leaving for work one morning two years ago when the accident occurred. The driver got probation.

In the latest on her slow and painful journey to find the person she used to be, Jackie went to
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Scientists create stem cells to help decipher diseases

Douglas A. Melton

Scientists have created stem cells from patients suffering from 10 incurable diseases, from Down syndrome to diabetes and Parkinson’s – immortal cells that might one day be turned into repair material for wasting muscles or damaged brains.
The Harvard University-led team has taken skin and bone marrow cells from diseased patients and re-programmed those cells to behave like cells from days-old embryos.

The feat allows scientists for the first time to watch muscular dystrophy and other diseases unfold in a petri dish, “that is, to watch what goes right or wrong,” said Doug Melton, co-director of the Harvard
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New Stem Cells Technique Offers Hope for Kids With Immune Deficiency

For children born with immunodeficiencies, researchers may have found a better way for them to get the help they need from stem-cell transplants (…)

Children with primary immunodeficiencies have genetic defects in their immune system that leave them open to infection and other complications. Stem-cell transplants can replace the defective immune system with one derived from healthy donor bone marrow, but without a stem-cell transplant, many of these children might die, the researchers noted in a journal news release.

In order to create space for the donor stem cells and prevent rejection, the patient usually undergoes chemotherapy, radiotherapy or both. This
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