Tag Archives: Gene

Israeli researchers discover method to neutralize tumor growth in embryonic stem cell therapy

Hebrew University of Jerusalem

Researchers at the Hebrew University of Jerusalem discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells, said the university on Wednesday.
The researchers’ work paves the way for further progress in the promising field of stem cell therapy, said the press release of the university sent to Xinhua.

According to the release, human embryonic stem cells are theoretically capable of differentiation to all cells of the mature human body (and are hence defined as “pluripotent“).
This ability, along with the ability to remain undifferentiated indefinitely in culture, make regenerative medicine using human
Read More…

Scientists create mammalian cells with single chromosome set

Researchers have created mammalian cells containing a single set of chromosomes in research funded by the Wellcome Trust and EMBO. The technique should allow scientists to better establish the relationships between genes and their function.

Mammal cells usually contain two sets of chromosomes – one set inherited from the mother and one from the father. The genetic information contained in these chromosome sets helps determine how our bodies develop. Changes in this genetic code can lead to or increase the risk of developing disease.

To understand how our genes function, scientists manipulate the genes in animal models – such as the
Read More…

ITALY – Rome, Universita’ Cattolica, lecture on intestinal and pancreatic stem cells

Image by Getty Images via Daylife

“The role of BMI1 in adult intestinal and pancreatic exocrine stem cells” is the name of the opening lecture of the 2008-2009 Biology Lectures promoted by the Institute of General Pathology at Università Cattolica in Rome, headed by Professor Tommaso Galeotti. The seminar will take place on Wednesday, March 18 at 3:00pm, in the Aula Moscati at the University in Rome (Biology Institute, Largo F. Vito 1), and will be led by Eugenio Sangiorgi, a researcher at the Institute of Medical Genetics for the university, and by the post-doctoral fellowship in the laboratory of
Read More…

Stem cells without genetic defects heralded as breakthrough

The prospect of treating genetic diseases with corrected stem cells grown from patients’ own bodies has moved closer, after the results of a remarkable experiment.

Scientists have successfully reprogrammed skin tissue from people with a rare form of anaemia to create powerful stem cells, while at the same time rectifying the genetic defect that causes the condition.

The corrected stem cells could be grown into blood precursor cells for therapy. As these would carry a patient’s own DNA, except for the mutation responsible for the illness, they could be transplanted without risk of rejection by the body’s immune system.

Though the research
Read More…

ITALY – Stem Cells. Zebrafish Provides Hope For Costello Syndrome Patients

Mental retardation, altered facial characteristics, and heart problems are all problems suffered by children affected by Costello syndrome, a genetic disease that is being studied by researchers in Milan at the Italian Foundation for Cancer Research (FIRC) Institute of molecular oncology (IFOM) using the zebrafish as a model.

The cause of the disease – explained the scientists in the January issue of ‘Disease Models & Mechanisms’ monthly magazine – is a mutation of the Ras gene, the same alteration observed in 20pct of tumors. One out of every five cases of cancer and the rare genetic disease have a common
Read More…