Tag Archive for 'Duke University'

Heart repair checked by mouse stem cells study

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Scientists have taken the first steps toward producing the “heart patch,” a design for a medical implement used to repair damage from heart disease, a new study suggests.

Last week, researchers from Duke University presented the results of a study which, using mouse embryonic stem cells, examined the way these cells develop into heart muscle, HealthDay News reports (…)

from http://www.privatemdlabs.com/news/Heart_Health_and_Cholesterol/Mouse-stem-cell-study-examines-heart-repair$19405309.php

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The Unimaginable Can Happen

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“Katrina is comparable in intensity to Hurrica...
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Hematologists are not typical “first responders,” and many feel ill-equipped to act in an emergency situation. Dr. Nelson Chao of Duke University hopes that those who attend the Emergency Preparedness Education Program Session this morning at 7:30 in La Nouvelle Ballroom C will feel more prepared to respond in times of crisis. Dr. Chao explains, “Preparation is an area that we don’t stress or think about enough, and we probably should. Our preparation would help both our patients and our staff in an emergency.” The session will include discussion of two recent crises and one hypothetical disaster that we will hopefully never face.

This year, the annual ASH meeting returns to New Orleans for the first time since Hurricane Katrina devastated the city. The effects of Hurricane Katrina were felt throughout the United States, but only those who lived through the natural disaster can truly understand its impact. Dr. Cindy Leissinger of Tulane University School of Medicine experienced the disaster first-hand and will share her unique perspective. She hopes that attendees will learn that the unimaginable can happen and that preparation can help in the recovery.

She will focus on the state of the medical community prior to Hurricane Katrina and what was learned from the disaster. One of her lessons involves the importance of communication. As she explains, “After Katrina, all of us were displaced — more than a million people were displaced — and that continued for many months for most of us. The most essential thing during that period for us as professionals and for our patients was the ability to communicate with each other. We had to scramble to put communication systems in place after Katrina — hopefully we learned some lessons that will help us to do a better job if another Katrina happens.” The lessons that Dr. Leissinger will present can be applied to other situations and are essential knowledge for all medical providers.

Questions about the H1N1 influenza outbreak from patients, families, and other providers are common for many hematologists this season. Some of these questions are relatively straightforward, including inquiries about the safety of vaccination and indications for prophylaxis. Other questions are more challenging, including how to vaccinate large patient populations efficiently, what to do when a staff member who has been at work becomes ill, and how to handle a worst-case scenario like an outbreak on a stem cell transplant unit. Dr. Richard Hatchett from the National Institute of Allergies and Infectious Disease will update the audience on the international H1N1 outbreak. He will address the current state of readiness and review public health measures. Dr. Hatchett’s expertise will be invaluable for hematologists and oncologists who care for populations vulnerable to influenza and other pathogens.

The session will conclude with Dr. Chao’s discussion of international preparedness for a potential radiological attack. Hematologists, oncologists, and experts in stem cell transplantation are uniquely qualified to care for survivors of a nuclear disaster and would be called on in such an emergency. International collaboration and preparation is necessary for the response to be effective. Dr. Chao will examine the nature of radiation injury and describe current international strategies for emergency response. In the event of a nuclear attack the response must be swift; preparation is essential. The unifying theme of preparedness promises to stimulate thought and discussion.

from http://www.hematology.org/Publications/ASH-News-Daily/2009/4627.aspx

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A Miracle for Aussie Toddler with Cerebral Palsy

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Adult Stem Cells Improve Young Boy with Cerebral Palsy

Corey de Gregorio, a 3 year old boy from Gordonvale, Australia has improved tremendously after going to a Stem Cell research company which implanted Adult Stem Cells from cord blood into him.

Corey’s parents, Mark and Roseanne had doubts before going to China for the stem cell treatment, but they  wanted Corey to have every chance to live a better life and therefore, they made the journey to China for the stem cell therapy which used only Adult Stem Cells.

The miracle treatment consisted of six “therapies” of cord blood stem cells.

Before the Adult Stem Cells for Cerebral Palsy

  • Had very little use of his left arm/hand
  • Little movement in his torso

After the Stem Cell Treatment

  • Can now use his left hand, can use it to drink a cup by himself
  • Increased flexibility in torso

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Stem cell donors getting more abundant

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On any given day, an estimated 6000 Americans who need a bone marrow transplant are searching the country’s donor banks hoping to find the right match.
For many of those patients, especially minorities, the odds of finding an outside donor have been pretty low. But, that is starting to change. There is new research that suggests the donor pool may be widening.

Just shy of his second birthday, little Elmor Bonilla has overcome obstacles and odds most people don’t face over a lifetime.
Elmor was born with Krabbe disease; a rare and often fatal disorder that attacks the central nervous system.
His best shot at survival is a bone marrow transplant immediately.

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USA – Umbilical Cord Stem Cells Increasingly Stored in Private Banks for Autologous Use

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Stem cells from umbilical cords are increasingly being stored in private banks for autologous use. “Newsweek” added to the debate writing about Dallas Hextell, who at the age of  8 months  was diagnosed with cerebral paralysis, a condition normally caused by serious neural damage due to oxygen deprivation in the uterus or at birth. His parents consulted various neurologists, but the possibility of a recovery was virtually non-existant.

About 9 months later, when given the opportunity to participate in a Duke University clinical study on autologous stem cell transplants (stem cells that are stored for later use by the same donor) the couple did not let the opportunity slip away. When Dallas was born, blood from his umbilical cord was removed for autologous use. His parents paid, like in Italy, to store the umbilical cord in a private bank.

A week after the transplant, Dallas suddenly started to speak, calling for his mother. Today he is 2 years old and is able to walk on his own and do the unthinkable for a child with cerebral paralysis. This story truely puts an interesting spin on the controversial topic of stem cell storage.

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Umbilical Cord Stem Cells, a Point in Favor of Autologous Storage

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Storing your children’s umbilical stem cells in private banks for autologous use is a growing trend. But is it an evil marketing ploy, a useless precaution, or a winning strategy? The debate rages on, but perhaps a report in Newsweek could shift the balance in favor of this practice.

When he was 9 months old, Dallas Hextall was diagnosed with cerebral paralysis, a serious neural disorder caused by oxygen deprivation in the uterus or at birth. His parents consulted many neurologists, but according to them, he boy’s chances for a recovery were almost non-existant.

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