Hundreds of thousands of people suffer from hereditary diabetes, a condition that destroys cells in the pancreas and leaves the body unable to regulate blood sugar levels.
Sufferers are forced to inject themselves with insulin everyday and adopt special diets to cope with the irreversible condition.
But now scientists claim a cure could be developed after cells in the liver were converted to insulin producers in research on mice.
They believe the process, described in the journal Developmental Cell, could one day lead to a permanent one-off cure for the disease.
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A new experimental therapy to treat diabetes, which involves transplanting embryonic pig stem cells into the diseased tissue, is currently being researched. Experiments have been done on primates, but the results that have been obtained indicate that in the future the same technique could be applied to human beings. For many years, pig organs have been considered the most best match to be used in human transplants, but strong immune reactions and powerful combinations of anti-rejection drugs have always represented an important obstacle in their clinical use.
A study published in the
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The hardship’s focus is on pilot studies conducted in China. Sean Hu, CEO and Chair of Shenzhen Beike Biotechnologies Co. Ltd. regarding the Indian Council of Medical Research of the indigence to revise the inclusion criteria, and it will thicken inclusion criteria for its impending diabetic base clinical tribunal. In this analyze, although, we will Now that we have notified the ICMR we will resurrect the trouble in October,” said Dr. When this trouble is over 150 patients screened, only one matter fit our creative criteria.” He went onto hint that diabetic bottom disease experienced in a
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Using skin cells from people with type 1 diabetes, researchers were able to produce cells that made insulin in response to changing blood sugar levels, though not as efficiently as normal insulin-producing cells do. (…) “This is a big deal,” said Susan Solomon, CEO of the New York Stem Cell Foundation, which provided some of the funding for the study. “Tackling the basic biology of type 1 diabetes, which is a very complex disease, is a critical step. With these cells, we can see in a dish what’s happening to the immune system, and if
Alan Lewis of the Juvenile Diabetes Research Foundation distinguishes type 1 and type 2 diabetes, and continues to explain how stem cells are being used today to develop new treatments for type 1 diabetes (a.k.a. juvenile diabetes). Human embryonic stem cells (hESC) are being differentiated to the beta (insulin producing) cells that type 1 diabetics lack, and are being transplanted , in animal models. Since type 1 diabetes is an auto-immune disease, the transplanted cells must be protect from destruction by the immune system. Currently, researchers are working towards that goal with encapsulating technologies and a “gentle” immuno-modulation. In