Tag Archives: DARPA

Pentagon scores first success in regenerating limbs in veterans

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The Pentagon has made its first significant development with ‘induced’ stem cells (stem cells not obtained from embryos) to regenerate the limbs of amputees who fought in the wars in Iraq and Afghanistan. Researchers were successful in transforming epithelial cells, which were manipulated to regress to their primordial state, into blastemas. A blastema is a mass of undifferentiated cells, which can develop into new body parts. In nature, blastemas are present in salamanders, and newts, animals, which are capable of restoring their own limbs with functionality after amputation.

The final goal, which is still far
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StemCells can avoid rejection from the immune system

Last year, Japanese researchers announced that the first human patient would be treated with induced pluripotent stem cells in an attempt to reverse a degenerative eye condition called macular degeneration that leads to vision loss.

Now, a team of scientists headed by biologists at UC San Diego has discovered how induced pluripotent stem (iPS) cells, which are derived from an individual’s own cells, could be programmed to avoid rejection from the immune system.

Their findings, published online ahead of print in the journal Cell Stem Cell, show that iPS cells can differentiate or change into various types of functional cells with
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