Tag Archive for 'Coronary artery bypass surgery'

Stem cells from surgery leftovers could repair damaged hearts

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Scientists have for the first time succeeded in extracting vital stem cells from sections of vein removed for heart bypass surgery. Researchers funded by the British Heart Foundation (BHF) found that these stem cells can stimulate new blood vessels to grow, which could potentially help repair damaged heart muscle after a heart attack.

The research, by Paolo Madeddu, Professor of Experimental Cardiovascluar Medicine and his team in the Bristol Heart Institute (BHI) at the University of Bristol, is published in the leading journal Circulation.

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‘Leftover’ veins from heart surgery yield stem cells

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A University of Bristol team extracted stem cells from the veins, then used them to stimulate new blood vessel growth in mice, Circulation reports.

The researchers say their findings could bring treatments to repair damaged heart muscle one step closer.

However, a stem cell expert warned that they remained some years away.

Stem cells are attractive to medical researchers because they have the ability to produce many different types of human cell, opening up the possibility of repair or renewal for tissues ravaged by disease or injury (…)

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Cardiac stem cell patient introduced

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Doctors with the University of Louisville and officials with Jewish Hospital Friday introduced the recipient of one of the world’s first adult cardiac stem cell infusion to treat congestive heart failure.

Michael Jones, 66, had his own cardiac stem cells injected directly into heart scar tissue, using a cardiac catheterization procedure, according to a news release.

Dr. Mark Slaughter, chief of the Division of Cardiothoracic Surgery at the University of Louisville and director of the Heart Transplant and Mechanical Assist Device Program at Jewish Hospital, performed coronary artery bypass surgery on Jones on March 23, according to the release.

Jones had congestive heart failure and permanent scarring of the heart resulting from multiple blocked arteries.
The cardiac stem cells injected into the scar tissue were removed from a portion of the upper chamber of Jones’ heart.

The tissue was sent to Harvard University and Brigham & Women’s Hospital in Boston, where the cardiac stem cells were grown.

The infusion was performed at Jewish Hospital by Dr. Sohail Ikram, a University of Louisville professor of medicine and director and chief of invasive and interventional cardiology at Jewish Hospital.

Leader of the study was Dr. Roberto Bolli, Jewish Hospital Heart and Lung Institute Distinguished Chair in Cardiology and director of the University of Louisville’s Institute for Molecular Cardiology.
In the release, Bolli said the intent of the injection is to help the heart regenerate tissue and function.
The university and Jewish Hospital continue to enroll patients in the U.S. Food and Drug Administration-approved clinical trial.

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