Tag Archives: Cornea

Corneal stem cells to give mom better vision

Debra Astrug was struggling. She couldn’t read or drive, she worried about crossing the street to get the mail, and she couldn’t draw (…)

Astrug needed a transplant, this time of corneal stem cells from a living donor to fix her limbal stem cell deficiency, which causes the cornea to be covered with abnormal tissue. She underwent the transplant in March 2013 at Loyola University Medical Center in Maywood and now has near-perfect vision with a therapeutic lens (…)

Astrug’s sister would have been an ideal candidate to donate the tissue, but she died in 2005 from stomach cancer. Next best
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Stem Cells Repair Damaged Corneas in Mice; Procedure may someday replace transplants in people

Image by GogDog via Flickr

Stem cells injected into the eyes of mice with defective corneas returned the corneas to a more normal appearance, a new study has found.

Researchers hope the procedure might one day be in humans. About 40,000 such transplants are done each year in the United States.

“The stem cells took the scar-like matrix, remodeled it and made it more like normal,” said senior investigator James Funderburgh, an associate professor of ophthalmology at the University of Pittsburgh. “We were surprised and delighted.”

A report on the study is in the April 9 online edition of the journal Stem Cells.

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Great Britain – Stem cells against blindness

Image via Wikipedia

From stem cells comes a ray of light for those who lives in the dark. A new surgical operation anti-blindness is under examimation by a team of Scottish scientists from Edinburgh and Glasgow, ready to start a study about using adult stem cells on 20 patients suffering of cornea blindness: this disease plague over than 80% of the senior citizens.

“We can note 2 or 3 new cases of cornea blindness every month; it’s a big problem” says Bal Dhillow from Princess Alexandra Eye Pavillon of Edinburgh.

The experimental technique contemplate using of adult stem cells taken from a
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Stem cells overcome major cause of blindness

Researchers have identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule that acts as a marker for hard-to-find limbal stem cells.

This work, a collaboration among the Harvard-affiliated Massachusetts Eye and Ear/Schepens Eye Research Institute, Boston Children’s Hospital, Brigham and Women’s Hospital, and the VA Boston Healthcare System, holds promise for burn patients, victims of chemical injury, and others with damaging eye diseases.

The research, published this week in the journal Nature,is also one of the first examples of constructing a tissue from an adult-derived human stem cell.

Limbal stem cells reside in the eye’s
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