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Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy.
The research, to be published in the June 5 issue of Cell Stem Cell, shows for the first time that a protein called Wnt7a increases the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle.
“This discovery shows us that by targeting stem cells to boost their numbers, we can improve the body’s ability to repair
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Sufferers from the debilitating bowel condition Crohn‘s disease may be cured using a groundbreaking stem cell treatment, according to the British doctor leading the research.
Initial findings from the world’s first controlled trial of the procedure have raised hopes that it could banish the disease’s symptoms for many years in up to half of the patients who undergo it.
The pioneering therapy involves “rebooting” the patient’s immune system, by first destroying the cells that have attacked it to cause the Crohn’s, and then replacing them.
Professor Chris Hawkey, a gastroenterologist at Nottingham University, is leading the Autologous Stem Cell Transplantation
Stem Cell Research Trial For Liver Patients Using Adult Stem Cells
In a stem cell research trial that isn’t getting enough news, liver patients are now being treated with their own Adult Stem Cells at Hammersmith Hospital in London, England. They have treated more than 30 patients now with “good results.” This […]
The central nervous system (CNS) contains a diverse set of neuronal subtypes, which together form the complex circuitry that regulates virtually every life function. To maintain normal body function, several systems in mammals require the simultaneous operation of a variety of neuronal subtypes, each sending different endocrine and paracrine messages to the brain. One such system is that of leptin signaling in the hypothalamus.
Leptin signaling regulates energy balance, glucose levels, food intake, and body weight. In recent work, Jeffrey Macklis, MD, Leader of HSCI’s Nervous System Diseases Program, introduced functional neurons into the hypothalami of mice with faulty leptin
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A biopolymer could aid in the regrowing of nerves induced by the use of stem cells according to a new research project that gives hope to people who have been in an accident and have lost the use of one or more limbs. The procedure will enter into clinical testing in January after animal testing has been completed.
The Experimental Neurological Institute (INSPE), founded in 2005 at San Raffaele Hospital of Milan became operational with the inauguration of more than 1,200 square meters of lab space entirely dedicated to general and clinical research therapies for