Tag Archives: Cellular differentiation

Stem cell treatment for alcoholics

Of all the alcoholic liver disease patients thronging the out-patient departments of the Post Graduate Institute of Medical Education and Research (PGIMER), nearly 50% are from Punjab.

What draws them to this institute is the stem cell treatment offered to the severe alcoholic hepatitis that acts as a boon.

PGI is the only tertiary hospital in the region which caters to this end-stage liver disease from Punjab, Himachal, Haryana and Chandigarh.

The stem cell treatment reports 78% success in cases of severe alcoholic hepatitis. A report on the same had been published in the prestigious American journal of gastroenterology this month. Moreover,
Read More…

From Stem Cells to Lung Cells

Bronchi, bronchial tree, and lungs. (Photo credit: Wikipedia)

How do you grow stem cells into lungs? The question has puzzled scientists for years. First you need the right recipe, and it took BU researchers Darrell Kotton, Tyler Longmire, and Laertis Ikonomou seven years of trial and error and painstaking science to come up with it. “A lot had to happen to make a lung,” says Kotton. “It was a little more complicated than Julia Child’s ‘heat, eat, bon appetit.’”

Kotton is a School of Medicine associate professor of medicine and pathology and codirector of the Center for Regenerative Medicine (CReM),
Read More…

What Decides Neural Stem Cell Fate?

A gene called SOX2 acts as a stem cell gatekeeper – only cells expressing it have the potential to become neurons.

Early in embryonic development, the neural crest – a transient group of stem cells – gives rise to parts of the nervous system and several other tissues. But little is known about what determines which cells become neurons and which become other cell types. A team led by Dr. Alexey Terskikh at Sanford-Burnham Medical Research Institute (Sanford-Burnham) recently found that expression of a gene called SOX2 maintains the potential for neural crest stem cells to become neurons in the
Read More…

MyoD Helps Stem Cells Proliferate in Response to Muscle Injury

The master regulator of muscle differentiation, MyoD, functions early in myogenesis to help stem cells proliferate in response to muscle injury, according to researchers at Case Western Reserve University.
The study appears online Jan. 4 in the Journal of Cell Biology.

London – Researchers find safer way to make stem cells

Image via Wikipedia

Researchers said on Sunday they had found a safer way to transform ordinary skin cells into powerful stem cells in a move that could eventually remove the need to use human embryos.
It is the first time that scientists have turned skin cells into induced pluripotent stem cells or iPS cells — which look and act like embryonic stem cells — without having to use viruses in the process.
The new method also allows for genes that are inserted to trigger cell reprogramming to be removed afterwards.
Stem cells are the body’s master cells, producing all the body’s tissues and
Read More…