The master regulator of muscle differentiation, MyoD, functions early in myogenesis to help stem cells proliferate in response to muscle injury, according to researchers at Case Western Reserve University.
The study appears online Jan. 4 in the Journal of Cell Biology.
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Researchers said on Sunday they had found a safer way to transform ordinary skin cells into powerful stem cells in a move that could eventually remove the need to use human embryos.
It is the first time that scientists have turned skin cells into induced pluripotent stem cells or iPS cells — which look and act like embryonic stem cells — without having to use viruses in the process.
The new method also allows for genes that are inserted to trigger cell reprogramming to be removed afterwards.
Stem cells are the body’s master cells, producing all the body’s tissues and
Researchers from the Center for Stem Cell Biology and Regenerative Medicine and the Department of Medicine at Thomas Jefferson University claim that a gene shown to play a role in the aging process appears to play a role in the regulation of the differentiation of embryonic stem cells.
In the study, published online in the journal Aging Cell, the researchers identified a protein interaction that controls the silencing of Oct4, a key transcription factor that is critical to ensuring that embryonic stem cells remain pluripotent. The protein, WRNp, is the product of a gene associated with Werner syndrome, an autosomal
Your hair may seem unwilling to cooperate some mornings, but at the root of each strand is a tiny partnership of stem cells that work very well together to make hair happen. New research from The Rockefeller University has elucidated how these adult stem cells communicate with each other to make hair grow and give it pigment.
“Deciphering the mechanisms behind stem cell differentiation advances our understanding of how adult stem cells can be used to maintain tissue integrity and heal wounds,” says Chiung-Ying Chang, a graduate student in the Laboratory of Elaine Fuchs, Rebecca C. Lancefield Professor
Of all the alcoholic liver disease patients thronging the out-patient departments of the Post Graduate Institute of Medical Education and Research (PGIMER), nearly 50% are from Punjab.
What draws them to this institute is the stem cell treatment offered to the severe alcoholic hepatitis that acts as a boon.
PGI is the only tertiary hospital in the region which caters to this end-stage liver disease from Punjab, Himachal, Haryana and Chandigarh.
The stem cell treatment reports 78% success in cases of severe alcoholic hepatitis. A report on the same had been published in the prestigious American journal of gastroenterology this month. Moreover,