Tag Archives: Cell biology

Stem Cells startup to fight ALS

USC Stem Cell researcher Justin Ichida has marshaled the expertise of pharmaceutical company Sanofi and startup DRVision Technologies, along with $1.5 million in federal funding, to find new drugs in the fight against amyotrophic lateral sclerosis, or Lou Gehrig’s disease.

ALS patients suffer from the death of the cells that transmit signals from the brain to the muscles, called motor neurons, leading to progressive paralysis and usually resulting in fatal respiratory failure within three to five years of diagnosis.

The three-year grant comes from the Department of Defense. Each year, the DoD funds two ALS Therapeutic Development Awards because military veterans
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Stem cell treatment for alcoholics

Of all the alcoholic liver disease patients thronging the out-patient departments of the Post Graduate Institute of Medical Education and Research (PGIMER), nearly 50% are from Punjab.

What draws them to this institute is the stem cell treatment offered to the severe alcoholic hepatitis that acts as a boon.

PGI is the only tertiary hospital in the region which caters to this end-stage liver disease from Punjab, Himachal, Haryana and Chandigarh.

The stem cell treatment reports 78% success in cases of severe alcoholic hepatitis. A report on the same had been published in the prestigious American journal of gastroenterology this month. Moreover,
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Gene key to develop stem cells

Researchers have found a gene that could be key to the development of stem cells — cells that can potentially save millions of lives by morphing into practically any cell in the body.

The gene, known as ASF1A, is at least one of the genes responsible for the mechanism of cellular reprogramming, a phenomenon that can turn one cell type into another, which is key to the making of stem cells.

Researchers at the Michigan State University analysed more than 5,000 genes from a human egg, or oocyte, before determining that the ASF1A, along with another gene known as OCT4 and
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Easier to develop life-saving stem cells

Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save millions of lives by morphing into practically any cell in the body.

The gene, known as ASF1A, was not discovered by the team. However, it is at least one of the genes responsible for the mechanism of cellular reprogramming, a phenomenon that can turn one cell type into another, which is key to the making of stem cells (…)

“This has the potential to
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Update on Phase I Adipose Stem Cell Trial

Bioheart Inc, a biotechnology company focused on the discovery, development and commercialization of autologous cell therapies, announces an update on the phase I safety trial using adipose derived cells.

Approximately four years ago in April, 2010, Bioheart initiated a study using adipose derived stem cells (AdipoCell(TM)) in congestive heart failure patients. In collaboration with the Regenerative Medicine Institute of Tijuana, Mexico, five congestive heart failure patients were successfully treated in the initial pilot trial at Hospital Angeles Tijuana. Patients underwent a mini-lipoaspiration procedure where 60ccs of fat were removed.

This fat was processed to obtain the stromal vascular fraction (SVF) which
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