Tag Archive for 'Cartilage'

Stem Cells Against False Joints

The Thin Red Line (1854 battle)
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Russian scientists started clinical trials of treating false joints by means of demineralized bone matrix with introduced mesenchymal stem cells of a patient.

False joints often occur as a complication during fractures of long bones, when splinters do not adhere, and cartilage layer forms between them. This layer is called false joint, and in this case, additional surgery is required to help a bone to heal.

Modern surgeons fight this problem with bone transplants, but bone recovery takes about one year. Possible solution is transplantation of mesenchymal stem cells of bone marrow, which can turn into various cells, including osteocytes. However, before differentiating cells require a substrate to attach to, and false joint has neither appropriate surface, nor nutrients for stem cells. In this case, the majority of stem cells dies or migrates away the desired place.

Russian scientists suggest putting stem cells on demineralized bone transplants, made of human long bones. Cell were extracted from patient’s bone marrow, cultivated in nutrient medium, and then inhabited bone matrix.

from Russia IC

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Stem cells from teeth

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“You can make liver. You can make pancreas. You can make bone. Therefore you can make neuro cells. You can make heart cells,” said Dr. Robert Carpenter
Yes, he said make a liver make a heart. From what? Stem cells from your teeth.

“We recently discovered that adult stem cells that don’t have the controversy related to it like embryonic cells have the ability to regenerate and treat a number of illnesses and injuries,” Carpenter said.
Stem cells are being studied to affect other disease like diabetes, kidney problems; liver problems even Parkinson’s disease. It’s in human clinical trials, and it is expected to be available within the next decade. Stem cells from teeth are proving much better than those from even bone marrow.

“With dental stem cells, since they are closely linked to bone and cartilage. It is easy to manipulate these immature cells into cartilage. They’ve actually in the laboratory, have made an exact human ACL,” said Carpenter.Baby teeth have the most viable cells.

“Stem cells in teeth particularly deciduous teeth or wisdom teeth and the follicles the surround wisdom teeth are very immature very plastic stem cells, plastic being the key word that are manipulable into a number of different tissue types,” the doctor said.
Wisdom teeth are also a great source of stem cells and that is why Abby DelGiacco is sending wisdom teeth to a lab to have them preserved with a program called Stemsave. Once her teeth are extracted, they are placed in a container, sealed in a temperature-controlled thermos and overnighted to a cryolab where her cells are preserved if she needs them.

“You never really know what is going to happen and never want to think about it but something you could awful disease and that is what this is for it is not only for degenerative neurological diseases. It is for tissue, bone muscle, tendons if I tear my ACL,” said DelGiacco.
Insurance doesn’t pay to store your stem cells there is a $590 set up laboratory fee and each year thereafter Abby will pay $100.

The cells are there if and when she needs them and studies are showing they maintain viability at least fifty years, probably more. And if you don’t have wisdom teeth left, don’t worry. All you need is one healthy tooth.

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