December 4, 2009- Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called “Twist” may be the proverbial red flag that can accurately distinguish stem cells that drive aggressive, metastatic breast cancer from other breast cancer cells.
Building on recent work suggesting that it is a relatively rare subgroup of stem cells in breast tumors that drives breast cancer, scientists have surmised that this subgroup of cells must have some very distinctive qualities and characteristics.
A team of doctors of haematology department of Nilratan Sircar Medical College and Hospital performed a blood stem cell transplantation on a patient wherein they successfully re-infused blood stem cells into a patient’s bloodstream on 30 January. The patient is suffering from a type of blood cancer known as multiple myeloma.
Mrs Bela Samanta, a resident of Burdwan, has been a patient of leukaemia for past one year. On 16 December she was admitted to the hospital in a critical condition. Doctors examined her and said there was a need for this transplantation, if the patient wanted to lead a
The body is a battle zone. Cells constantly compete with one another for space and dominance. Though the manner in which some cells win this competition is well known to be the survival of the fittest, how stem cells duke it out for space and survival is not as clear. A study on fruit flies published in the October 2 issue of Science by Johns Hopkins researchers describes how stem cells win this battle by literally sticking around.
“Our work exemplifies how one signal coordinately maintains two types of stem cells in a single niche, or microenvironment,” says Erika Matunis,
Image by pablocanateam via Flickr
Research in Italy, in the coming years, will suffer much more compared to research in other countries, because, explained a study on the future of biomedical research in Italy described yesterday in Siena by Stefano Palumbo, “the national debate on bioethical issues will continue to be affected by pre-established ideological positions, and often, will be aimed at imposing limits on scientific research”.
Due to the overwhelming “majority of Catholic members in the National Bioethics Committee, Italy will be,” according to the study, “the most conservative country in the world regarding stem cells,” which will result in
A team at Keio University has used stem cells to cure mice whose hind legs were paralyzed due to spinal cord damage, the researchers reported Wednesday at a Tokyo symposium.
The team transplanted neural stem cells grown from human iPS cells.
Team leader Hideyuki Okano, a physiology professor at Keio, said it is the first time in the world in which the curative effects of “induced pluripotent stem cells,” or iPS cells, have been confirmed.
Currently, there is no effective treatment for spinal nerve damage and treatment using iPS cells gives hope of a cure.
“It is valuable that treatment using human iPS