The first operations have been successfully performed at Seriate Hospital (Bergamo) using autologous stem cell transplants to rebuild a part of the breast after removing a tumor. The technique used in the operation is known as ‘lipofilling’, which calls for some of the patient’s abdominal fat to be removed in a procedure similar to liposuction. The fat is then purified and manipulated in the laboratory to concentrate stem cells as much as possible, then they are transplanted into the portion of the breast that has been removed to eliminate the cancer.
Research has indicated that certain sarcomas come from the mesenchymal stem cells. However, expression of neural stem cells has been noted in others. Identifying and isolating mesenchymal stem cells and neural stem cells relies on finding specific proteins expressed by both types.
In this study, eight different markers representing proteins associated with these two types of stem cells were applied to the 81 tumors. Through cluster analysis, the researchers organized the data into groups showing similar patterns. Two major subgroups of pediatric sarcomas emerged
Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus their efforts on cancer; the third will search for ways to accelerate the healing of large bone fractures.
The free screens will take place at the Choi Family Therapeutic Screening Facility, part of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. Andrew McMahon, director of the stem cell research center, is sponsoring the bone repair project, and Stephen Gruber, director of
Scientists at the John Innes Centre in Norwich, UK, have shown how plants can protect themselves against genetic damage caused by environmental stresses. The growing tips of plant roots and shoots have an in-built mechanism that, if it detects damage to the DNA, causes the cell to ‘commit suicide’ rather than pass on its defective DNA.
Plants have, at the very tips of their roots and shoots, small populations of stem cells, through which they are able to grow and produce new tissue throughout the plant’s life. These stem cells are the precursors to producing plant tissues and
Making a breakthrough in the battle against breast cancer, scientists have used a combination of drugs to target cancer stem cells that cause the disease to spread.
Current treatments kill only the surface cells in a breast tumour, but scientists now say they can destroy the root, the Mirror reported.
They hope that the findings, revealed ahead of World Cancer Day, can be used to help women with advanced and aggressive cancers. Targeting cancer stem cells takes us a step closer to better clinical options for those with the disease, said Dr Rob Clarke, of Manchester University.