Tag Archives: Calorie

Calorie Restriction and Skeletal Muscle Stem Cells

While looking for mechanisms that might be relevant to restoring regenerative potential in older skeletal muscle, HSCI Executive Committee member, Amy Wagers, PhD, and her team, thought about mechanisms that had been studied for a long time evolutionarily as regulating lifespan and longevity. One example of such a mechanism is reduced calorie intake in the absence of malnutrition, also know as calorie restriction, which has been show to extend lifespan in many organisms.

In order to address the question of whether calorie restriction could also affect skeletal muscle regeneration, Wagers and her colleagues placed mice for 12 weeks
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