“Latest Stem Cells News”

Steve Jones

We have been told for almost a decade that stem cells are the future of medicine: that these tiny clumps of tissue could become a biological “repair kit”, able to regenerate or heal almost any part of the body. But amid all the prophecies of patches for damaged hearts, new nerve cells for spinal injuries or stroke victims, and insulin-producing cells for diabetics, few people predicted that it would be British-based scientists who would be leading the way in mapping out this new terrain.

Writing in The Daily Telegraph last week, Professor Steve Jones bemoaned the failure of genetic research to deliver on its promises. Yet no such complaint could be made about stem cells, the “prototype” cells that are capable of growing into any of the 300 different kinds of cell in the body. As they make the leap from the lab to the clinic, new breakthroughs and developments are emerging from British universities on an almost weekly basis. Scientists, normally hesitant to overstate the significance of any work, are starting to talk about a new era of medicine.

“The technology has come of age a lot faster than people expected,” says Professor Pete Coffey of University College London. “We all saw this as a technology that had potential for clinical application, but it has gone very quickly down that route.”

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A STEM cell therapy offering “natural” breast enlargement is to be made available to British women for the first time.
The treatment could boost cup size while reducing stomach fat. It involves extracting stem cells from spare fat on the stomach or thighs and growing them in a woman’s breasts. An increase of one cup size is likely, with the potential for larger gains as the technique improves.

A trial has already started in Britain to use stem cells to repair the breasts of women who have had cancerous lumps removed. A separate project is understood to be the first in Britain to use the new technique on healthy women seeking breast enlargement.
Professor Kefah Mokbel, a consultant breast surgeon at the London Breast Institute at the Princess Grace hospital, who is in charge of the project, will treat 10 patients from May. He predicts private patients will be able to pay for the procedure within six months at a cost of about 6,500 pounds (about 9200 USD).

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British team pioneers reconstruction technique using enriched tissue

A remarkable reconstruction technique is being trialled by British surgeons, who are harvesting stem-cell-enriched fat from women’s bodies to plug the dip often left by breast cancer operations.
The procedure appears to restore the softness and suppleness of breast tissues, undoing the damage frequently caused by lumpectomy and radiotherapy. Early signs indicate that it also eases the considerable pain with which patients are often left after treatment.

More than 31,000 women a year in Britain with early-stage breast cancer undergo operations in which just the lump and a healthy margin of tissue around it are removed. The cavity left in the breast following surgery can vary from a dimple to a mini-crater, but the dip invariably becomes more pronounced following radiotherapy, which most patients need. Irradiation damages the blood supply to the breast and shrinks and toughens overlying skin so that it sticks to the chest wall. Nerves can get trapped in the resulting scar tissue, causing constant discomfort. Although some surgeons have had short-term success with simple fat transfers – liposuctioning fat from elsewhere and injecting it into the breast hollow – the blob of fat struggles to get a decent blood supply.

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