Tag Archives: Breast cancer

Stem cells to grow bigger breasts

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A STEM cell therapy offering “natural” breast enlargement is to be made available to British women for the first time.
The treatment could boost cup size while reducing stomach fat. It involves extracting stem cells from spare fat on the stomach or thighs and growing them in a woman’s breasts. An increase of one cup size is likely, with the potential for larger gains as the technique improves.

A trial has already started in Britain to use stem cells to repair the breasts of women who have had cancerous lumps removed. A separate project is understood to be the
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Scientists reprogram cancer cells with low doses of epigenetic drugs

Experimenting with cells in culture, researchers at the Johns Hopkins Kimmel Cancer Center have breathed possible new life into two drugs once considered too toxic for human cancer treatment. The drugs, azacitidine (AZA) and decitabine (DAC), are epigenetic-targeted drugs and work to correct cancer-causing alterations that modify DNA.

The researchers said that the drugs also were found to take aim at a small but dangerous subpopulation of self-renewing cells, sometimes referred to as cancer stem cells, which evade most cancer drugs and cause recurrence and spread.

In a report published in the March 20 issue of Cancer Cell, the Johns Hopkins
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Source of cancer stem cells’ resistance to radiation discovered at Stanford

Much to the dismay of patients and physicians, cancer stem cells — tiny powerhouses that generate and maintain tumor growth in many types of cancers — are relatively resistant to the ionizing radiation often used as therapy for these conditions. Part of the reason, say researchers at Stanford University School of Medicine, is the presence of a protective pathway meant to shield normal stem cells from DNA damage. When the researchers blocked this pathway, the cells became more susceptible to radiation.

“Our ultimate goal is to come up with a therapy that knocks out the cancer stem cells,” said Robert
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New drug combo can destroy root of breast cancer cells

Making a breakthrough in the battle against breast cancer, scientists have used a combination of drugs to target cancer stem cells that cause the disease to spread.

Current treatments kill only the surface cells in a breast tumour, but scientists now say they can destroy the root, the Mirror reported.

They hope that the findings, revealed ahead of World Cancer Day, can be used to help women with advanced and aggressive cancers. Targeting cancer stem cells takes us a step closer to better clinical options for those with the disease, said Dr Rob Clarke, of Manchester University.

One Compound Detects and Treats Malignant Tumors and Certain Cancer Stem Cells

Madison, Wisconsin – More than a decade of laboratory research at the University of Wisconsin has proven that a single chemical compound may both detect and treat malignant tumors and certain cancer stem cells.
In three posters presented at the annual meeting of the American Association for Cancer Research (AACR) in Chicago, March 31-April 4, UW-Madison researchers describe exciting advances involving CLR1404, described as a “diapeutic” agent that can both image and destroy a wide range of malignant tumors and the one type of cancer stem cells examined so far.

The presentations are based on basic research in the lab of
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