(…) The investigators looked at two types of brain cells: adult neural stem cells, responsible for maintaining supplies of neurons and their supporting cells, and forebrain neurons, vital for performing complex cognitive tasks.
In The EMBO Journal, they reported that NAD (Nicotinamide adenine dinucleotide) levels decreased with age in the mouse hippocampus, a vital region of the brain for cognition. The researchers then used genetic techniques to find out what would happen when NAD manufacturing is turned off in the adult neural stem cells of the mouse brain.
“Neural stem cells are very metabolically expensive, so you might expect them to be
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Memorial Hermann-Texas Medical Center in Houston announced this morning it has done the nation’s first stem cell transplant to successfully treat a stroke patient.
The patient came to the hospital last Wednesday, too late to receive clot-busting drugs to treat the stroke, according to a news release about the procedure. So doctors decided to try a therapy they are investigating as part of a clinical trial with the University of Texas Medical School at Houston: using stem cells from the patient’s own bone marrow. The adult stem cells — not controversial embryonic stem cells — came from marrow
For years, researchers seeking new therapies for traumatic brain injury have been tantalized by the results of animal experiments with stem cells. In numerous studies, stem cell implantation has substantially improved brain function in experimental animals with brain trauma. But just how these improvements occur has remained a mystery.
Now, an important part of this puzzle has been pieced together by researchers at the University of Texas Medical Branch at Galveston. In experiments with both laboratory rats and an apparatus that enabled them to simulate the impact of trauma on human neurons, they identified key molecular mechanisms by which implanted
After much hope and controversy, for the first time stem cells have proven to have the ability to cure blindness.
The news comes from a study on age-related macular degeneration (AMD) of the retina, the most common cause of blindness in individuals over the age of 50.
The Sunday Times reports that the treatment was developed by a group of British researchers, who say that in the next six to seven years the treatment will become a routine operation, which will not last more than an hour.
The treatment involves the replacement of a layer of degenerated cells with new cells created
Progress has been made against strokes thanks to stem cells. British researchers, thanks to these cells, have managed to repair brain tissue damaged by a stroke. The study, financed by the research council on biological and biotechnological sciences of the United Kingdom, was published in Nature Biomaterials. The team from the Institute of Psychiatry at the University of Nottingham, used a biodegradable polymer called Plga to build a scaffold for neural cells.
Using these they filled the cavity left by a stroke. This allows, explained Mike Modo, psychiatrist at King’s College in London and coordinator of