Tag Archives: Brain

Stem Cell Therapy for Blindness receives global validation

In 2010, L V Prasad Eye Institute (LVPEI) moved away from culturing corneal stem cells in a petri-dish in the laboratory to directly culturing and expanding them on the patient’s eye.

This ingenuous technique was termed Simple Limbal Epithelial Transplantation (SLET) to contrast it from the radical tissue transplants and complex culture techniques that were the standard of care at that time.

SLET completely eliminates the need for laboratory based processing thereby making it possible to be executed by any well trained surgeon anywhere (…)

A pilot clinical trial was done on a small sample size including 125 patients, 65 adults and 60
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New Clues to Cognitive Decline

(…) The investigators looked at two types of brain cells: adult neural stem cells, responsible for maintaining supplies of neurons and their supporting cells, and forebrain neurons, vital for performing complex cognitive tasks.

In The EMBO Journal, they reported that NAD (Nicotinamide adenine dinucleotide) levels decreased with age in the mouse hippocampus, a vital region of the brain for cognition. The researchers then used genetic techniques to find out what would happen when NAD manufacturing is turned off in the adult neural stem cells of the mouse brain.

“Neural stem cells are very metabolically expensive, so you might expect them to be
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Texas hospital touts first successful stem cell transplant for stroke patient

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Memorial Hermann-Texas Medical Center in Houston announced this morning it has done the nation’s first stem cell transplant to successfully treat a stroke patient.

The patient came to the hospital last Wednesday, too late to receive clot-busting drugs to treat the stroke, according to a news release about the procedure. So doctors decided to try a therapy they are investigating as part of a clinical trial with the University of Texas Medical School at Houston: using stem cells from the patient’s own bone marrow. The adult stem cells — not controversial embryonic stem cells — came from marrow
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Scientists learn how stem cell implants help heal traumatic brain injury

For years, researchers seeking new therapies for traumatic brain injury have been tantalized by the results of animal experiments with stem cells. In numerous studies, stem cell implantation has substantially improved brain function in experimental animals with brain trauma. But just how these improvements occur has remained a mystery.

Now, an important part of this puzzle has been pieced together by researchers at the University of Texas Medical Branch at Galveston. In experiments with both laboratory rats and an apparatus that enabled them to simulate the impact of trauma on human neurons, they identified key molecular mechanisms by which implanted
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GREAT BRITAIN – Embryonic stem cells cure blindness in an hour

After much hope and controversy, for the first time stem cells have proven to have the ability to cure blindness.

The news comes from a study on age-related macular degeneration (AMD) of the retina, the most common cause of blindness in individuals over the age of 50.

The Sunday Times reports that the treatment was developed by a group of British researchers, who say that in the next six to seven years the treatment will become a routine operation, which will not last more than an hour.

The treatment involves the replacement of a layer of degenerated cells with new cells created
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