Tag Archives: Bone marrow

Hysterectomies a stem cell source

Discarded fallopian tubes from hysterectomies could be a good source of donor stem cells, say researchers.
Work shows they are an abundant source of the immature cells that have the potential to become a variety of the body’s tissues, like muscle and bone.

The discovery offers another “ethical” route to creating stem cell treatments for diseases like arthritis without using embryos.
The findings are published in The Journal of Translational Medicine.
Experts have already shown that getting mesenchymal stem cells from umbilical cords, menstrual blood, teeth and fat tissue is viable.

Discarded tissue

The latest work by a Brazilian team from the University of São
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Blood Vessel Cells Are Key to Growing Unlimited Amounts of Adult Stem Cells

Howard Hughes Medical Institute (HHMI) scientists have discovered that endothelial cells, the building blocks of the vascular system, keep blood stem cells dividing healthily in a lab dish much longer and more effectively than previous methods of growing the cells. The new advance dramatically improves scientists’ ability to manufacture large quantities of authentic adult blood stem cells, which may help revolutionize the field of bone marrow transplantation.

Shahin Rafii, an HHMI investigator at Weill Cornell Medical College in New York City, and his colleagues report on the development of an endothelial cell platform that supports self-renewal of the blood stem
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Stem Cells – Bone marrow can cure blood disorders

A leading specialty hospital has demonstrated that bone marrow stem cells can cure blood disorders like leukemia, thalassemia and aplastic anemia, a bone marrow failure.

“Bone marrow transplant has emerged as an effective cure for cancerous and genetic blood diseases through transfusion of its stem cells from a healthy donor to an affected patient,” Narayana Health City consultant hematologist Sharat Damodar told reporters here Tuesday.

The corporate hospital in the city’s southern suburb claims to have performed about 300 bone marrow transplants with over 80 per cent success rate.
Bone marrow can be collected from a related donor (siblings), matched unrelated donor

(non-family
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Research shows how snorting can deliver stem cells to the brain

William H. Frey

Scientists have pioneered a unique delivery system to administer therapeutic stem cells to the brain, by way of a simple nasal spray. Once the droplets containing the stem cells are snorted through the nose, the solution breaks through the blood-brain barrier, seeding the brain with the stem cells (…)

Scientists from the University of Minnesota and the University Hospital of Tuebingen, Germany conducted the research. The researchers administered the nasal spray containing rat stem cells to mice and within an hour, the rat stem cells were visible in the mice brains. The researchers then repeated the experiment
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Study shows that delivering stem cells improves repair of major bone injuries in rats

Image via Wikipedia

A study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.
The study shows that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation and better mechanical properties compared to treatment with the scaffold alone. This type of therapeutic treatment could be a potential alternative to bone grafting operations.

“Massive bone injuries are among the most challenging problems that orthopedic surgeons face, and they are commonly seen as a result of accidents as well as in soldiers returning
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