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ITALY – Campobasso. Amputation Avoided Using Patient’s Own Bone Marrow Stem Cells

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Bone marrow harvest
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A woman received a transplant of her own bone marrow stem cells, was able to avoid an amputation, and has started to walk again following an operation performed at Catholic University in Campobasso. This is one of the few such operations performed in Europe on the cardiovascular system using adult stem cells. The results were announced yesterday, about a month after the operation, and it is now clear that it will not be necessary to amputate the woman’s leg. “We can say that the operation was a complete success surgically,” said doctors that worked under Francesco Alessandrini, the director of the Cardiovascular Disease Department. It was a team effort thanks to the collaboration of the Hematology Unit led by Sergio Stroti, the Medical Images Department led by Giuseppina Sallustio, the laboratory led by Bruno Zappacosta, and the Anaesthesia and Intensive Therapy Unit led by Marco Rossi.

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Pennsylvania hospital in Gamida-Teva stem cell study

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City of Pittsburgh
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Western Pennsylvania Cancer Institute’s Dr. Entezam Sahovic: We are hopeful that this new technology will enable us to help more patients in need of transplants.

A joint venture between Gamida Cell and Teva Pharmaceutical Industries Ltd. will carry out a study at Western Pennsylvania Hospital (WPH). WPH is currently enrolling patients for the study.
The ExCell study will assess the safety and efficacy of StemEx as a treatment for hematological malignancies, including leukemia and lymphoma, in a single arm, global, pivotal registration study.
StemEx is a graft of expanded stem/progenitor cells, derived from a single unit of umbilical cord blood and transplanted in combination with non expanded cells from the same unit. It is being developed by a joint venture equally owned and managed by Gamida Cell and Teva.

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INDIA – first public stem cell bank opens in city

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Umbilical cord of a three-minute-old child.  A...
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CHENNAI -  The country’s first public stem cell bank, which would store stem cells extracted from a newborn’s umbilical cord for common use, was inaugurated here on Thursday. The cells, which are collected from the blood from umbilical cord soon after childbirth, are preserved at -196 degrees Celsius in liquid nitrogen.

While mothers can store the blood for private use for a cost, they would be charged nothing if they donate it to the public bank. These cells are capable of developing into different kinds of cells and tissues, offering new treatment methods for serious disorders including blood cancer.

Member of parliament Kanimozhi inaugurate , a unit of Jeevan Blood Bank. “Stem cells have a shelf life of 21 years. As of now, there is 80% cure from stem cell therapy for diseases like blood cancer and Thalassemia. In the future, it may be possible to use these cells to grow damaged tissues or organs. It has a potential of curing more than 70 medical conditions,” said Dr P Srinivasan, managing trustee, Jeevan Blood Bank.

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