When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer.
Now, a team of researchers led by biologists at the California Institute of Technology (Caltech) has found that, in mouse models, the molecule microRNA-146a (miR-146a) acts as a critical regulator and protector of blood-forming stem cells (called hematopoietic stem cells, or HSCs) during chronic inflammation, suggesting that a deficiency of
Don’t worry about your child’s loss of teeth or if they have immature ones as doctors at AIIMS can regrow them using stem cell technique by just making a minute slit in their root.
“We at AIIMS are treating children with infected, immature teeth as a result of traumatic injuries, by using locally available indigenous stem cells,” Dr Naseem Shah, Chief of the Centre for Dental Education and Research, AIIMS said.
She explained that the root forms the most important part of the tooth. It anchors the tooth within the bone and houses the pulp (tiny blood vessels and nerves) which
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A University of Bristol team extracted stem cells from the veins, then used them to stimulate new blood vessel growth in mice, Circulation reports.
The researchers say their findings could bring treatments to repair damaged heart muscle one step closer.
However, a stem cell expert warned that they remained some years away.
Stem cells are attractive to medical researchers because they have the ability to produce many different types of human cell, opening up the possibility of repair or renewal for tissues ravaged by disease or injury (…)
In 2010, L V Prasad Eye Institute (LVPEI) moved away from culturing corneal stem cells in a petri-dish in the laboratory to directly culturing and expanding them on the patient’s eye.
This ingenuous technique was termed Simple Limbal Epithelial Transplantation (SLET) to contrast it from the radical tissue transplants and complex culture techniques that were the standard of care at that time.
SLET completely eliminates the need for laboratory based processing thereby making it possible to be executed by any well trained surgeon anywhere (…)
A pilot clinical trial was done on a small sample size including 125 patients, 65 adults and 60
A two-year-old Delhi boy suffering from thalassemia got a new lease of life after a Bangalorean donated his blood stem cells to him. This is the first reported case in India of a thalassemia patient receiving blood stem cells from an unrelated donor.
Garvit Goel was advised to go for a blood stem cell transplant a year ago. None of his family members qualified to be potential donors. That’s when Sumeet Mahjan, a software professional from MindTree, stepped in.
For Sumeet, the turning point came in 2011 when his colleague’s 11-year-old son was diagnosed with leukemia. MindTree requested Datri, an NGO