Tag Archives: Blood vessel

Human Heart Can Make New Cells – Discovery could lead to ways of regrowing damaged cardiac tissue

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Solving a longstanding mystery, scientists have found that the human heart continues to generate new cardiac cells throughout the life span, although the rate of new cell production slows with age.
The finding, published in the April 3 issue of Science, could open a new path for the treatment of heart diseases such as heart failure and heart attack, experts say.

“We find that the beating cells in the heart, cardiomyocytes, are renewed,” said lead researcher Dr. Jonas Frisen, a professor of stem cell research at the Karolinska Institute in Stockholm, Sweden. “It has previously not been known whether
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‘Leftover’ veins from heart surgery yield stem cells

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A University of Bristol team extracted stem cells from the veins, then used them to stimulate new blood vessel growth in mice, Circulation reports.

The researchers say their findings could bring treatments to repair damaged heart muscle one step closer.

However, a stem cell expert warned that they remained some years away.

Stem cells are attractive to medical researchers because they have the ability to produce many different types of human cell, opening up the possibility of repair or renewal for tissues ravaged by disease or injury (…)

Stem Cells Transplanted From Marrow Into Heart May Improve Heart’s Performance

Concha Herrera Arroyo, from El Pais

The Cardiology department and the Area of Cell Therapy of Cordoba hospital Reina Sofia are carrying out clinical tests with patients who have suffered from a severe heart attack. With the implantation of the patient’s stem cells, the heart regenerates thus improving its wall motion, that is, its cardiac performance.

Indeed for the last four years, the Area of Cell Therapy of Cordoba hospital, led by haematologist Dr. Concha Herrera, has been implementing a therapy program with adult stem cells in patients with heart-related problems. However, this therapy is not a service the hospital
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ITALY – Campobasso. Amputation Avoided Using Patient’s Own Bone Marrow Stem Cells

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A woman received a transplant of her own bone marrow stem cells, was able to avoid an amputation, and has started to walk again following an operation performed at Catholic University in Campobasso. This is one of the few such operations performed in Europe on the cardiovascular system using adult stem cells. The results were announced yesterday, about a month after the operation, and it is now clear that it will not be necessary to amputate the woman’s leg. “We can say that the operation was a complete success surgically,” said doctors that worked
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MIT team’s nanoparticles could become a safer alternative to gene therapy delivered by viruses

About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT’s Daniel Anderson and Robert Langer for gene therapy, the insertion of genes into living cells for the treatment of disease. Sawicki was working on treating ovarian cancer by delivering — through viruses — the gene for the diphtheria toxin, which kills tumor cells (…)