Stem cells – unspecialized cells that have the potential to develop into different types of cells – play an important role in medical research. In the embryotic stage of an organism’s growth, stem cells develop into specialized heart, lung, and skin cells, among others; in adults, they can act as repairmen, replacing cells that have been damaged by injury, disease, or simply by age.
Given their enormous potential in future treatments against disease, the study and growth of stem cells in the lab is widespread and critical. But growing the cells in culture offers numerous challenges, including the constant need
All those who have suffered ligament damage could benefit from artificial ligaments built biologically. But, experimentation on artificial ligaments, which could come from stem cells and naturally replace damaged tissue, will not continue. Speaking about the issue was Luigi Ambrosio, one of the researchers of the Institute of Technology of Composite Material of the National Research Council (CNR) in Naples, who contributed to the realization of this biological ligament. Two solutions were proposed by the Neapolitan laboratory.
One solution was to build a biodegradable structure out of hyaluronic acid, one of the components of ligament
Shelley Brown was pointing toward a life of cutting-edge stem cell research. Then one day in 2010, she says, she encountered the divine.
“Something was moving, and I thought I must have hit the petri dish by accident,” said Brown, who had been trying to direct a set of stem cells toward bone cells during her Ph.D. work in biomedical engineering at the University of Michigan. “When I looked closer under the microscope, I realized the cells were beating. They had spontaneously differentiated into electrically coupled, beating heart cells. That’s when I felt at the mercy of God, and that’s
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Stem cell researchers have a lot of big dreams, and one is to someday regenerate damaged hearts. That is still many years away from becoming a commercial reality, if ever, but a few University of Washington scientists have formed a new company that hopes to make cells that can replace pacemakers, and someday rebuild damaged heart tissue that people are left with after heart attacks.
The company, Bellevue, WA-based Beat BioTherapeutics, is the brainchild of Chuck Murry and Michael Laflamme, a pair of UW stem cell researchers, and UW bioengineering professor Buddy Ratner. It has roots in about
University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings stem cell therapies another step closer.
To prove the cells’ regenerative powers, bone cells grown on this surface were then transplanted into holes in the skulls of mice, producing four times as much new bone growth as in the mice without the extra bone cells.
An embryo’s cells really can be anything they want to be when they grow up: organs, nerves, skin, bone, any type of human cell. Adult-derived “induced” stem