What is a neural stem cell? How can they help treat neurological disorders such as Alzheimer’s disease, Parkinson’s disease, spinal cord injury, stroke, ALS (Lou Gehrig‘s Disease)? Evan Snyder of the Burnham Institute helps define neural stem cells (NSC), explaining that they are relatively inaccessible in the adult patient, but that they seem to benefit from some immunotolerance.
It follows that we may be able to use readily available lines of embryonic stem cells for therapy in neurodegenerative disease. Evan reviews current clinical applications for neural stem cells (including as a vehicle for small molecule delivery), and gives his
The first world bank storing stem cells taken from amniotic fluid is “made in Italy”: it’s a private hospital in Busto Arsizio, near Milan.
Women planning amniocentesis – removal of amniotic fluid from the uterus (test done during pregnancy) – can ask for the “conservation set”, which will be given to the gynaecologist.
3 millilitre of amniotic liquid are enough to find some particular kind of stem cells very close to embryonic stem cells and suitable for in vitro breeding.
Then the test tube will be sent to the company which will store it for 20 years at -320°F.
Researchers and using stem cells as tools for disease study, drug screening, clinical trial strategy, and personalized medicine. The induced Pluripotent Stem cell (iPS) is giving us a chance to rethink the way we are developing new drugs. These iPS cells are usually created from somatic cells (such as skin), and not embryos or adult stem cells. In creating iPS from patients’ diseased cells, scientists can study the disease in vitro, looking for disease phenotypes, applying microenvironmental stress, and testing new drugs. Compared to animal model testing (e.g. mice), this represents a significant breakthrough, that can be used to
The body is a battle zone. Cells constantly compete with one another for space and dominance. Though the manner in which some cells win this competition is well known to be the survival of the fittest, how stem cells duke it out for space and survival is not as clear. A study on fruit flies published in the October 2 issue of Science by Johns Hopkins researchers describes how stem cells win this battle by literally sticking around.
“Our work exemplifies how one signal coordinately maintains two types of stem cells in a single niche, or microenvironment,” says Erika Matunis,
Vet-Stem Inc. announced that over 8000 animals have now been treated with Vet-Stem cell therapy.
Vet-Stem began providing stem cells to veterinarians in 2004 and has now provided stem cells for the treatment of over 8,000 animals. Vet-Stem was the first company to introduce rapid turnaround stem cell services in the US.
After providing stem cells for thousands of horses, Vet-Stem pioneered stem cell therapy in dogs and cats and is now the world leader in Regenerative Veterinary Medicine. The rapid adoption of stem cell therapy by equine veterinarians and horse owners provided a springboard for use in small animal veterinary