Tag Archives: Biology

ITALY – Undersecretary Fazio: against freedom of choice for autologous conservation of children’s stem cells by parents

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Italian Welfare Undersecretary Ferruccio Fazio disapproves of private biobanks and is clearly in favor of the “allogenic” conservation of umbilical cord stem cells, meaning the conservation of stem cells saved for the exclusive use of the donor-patient. Speaking about a government report on “the appropriate use of umbilical cord stem cells”, Fazio outlined the government’s approach on the issue. A few weeks after a ministerial decree dictating new regulations for umbilical cord conservation, Fazio explained autologous donation, meaning conservation of stem cells for yourself, “is not only less useful, but also less efficient as
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Scientists Create Stem Cells From Eggs Of Aging Mice

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Researchers at NYU Langone Medical Center have created stem cells from the eggs of aging mice that could be used for reproductive purposes and regenerative medicine. The study, published in April issue of Aging Cell, found that even though the eggs from older females were slightly less efficient at making stem cells than those from younger females, the capacity to create stem cells was sustained.

CD133 (Prominin) Negative Human Neural Stem Cells Are Clonogenic and Tripotent

CD133 (Prominin) is widely used as a marker for the identification and isolation of neural precursor cells from normal brain or tumor tissue. However, the assumption that CD133 is expressed constitutively in neural precursor cells has not been examined.

Methodology/Principal Findings

In this study, we demonstrate that CD133 and a second marker CD15 are expressed heterogeneously in uniformly undifferentiated human neural stem (NS) cell cultures. After fractionation by flow cytometry, clonogenic tripotent cells are found in populations negative or positive for either marker. We further show that CD133 is down-regulated at the mRNA level in cells lacking CD133 immunoreactivity. Cell cycle
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Growing Spinal Discs, in Stem Cell Journal

Two professors made Clarkson University history when their research on stem cells was published in a prestigious journal from Cell Press.

Professor Thomas Lufkin, the Bayard and Virginia Clarkson Endowed Chair in Biology (left); and Research Assistant Professor of Biology Petra Kraus.Professor Thomas Lufkin, the Bayard and Virginia Clarkson Endowed Chair in Biology, and Research Assistant Professor of Biology Petra Kraus published a research paper in Cell Stem Cell on transforming cells into embryonic stem cells.

Professors strive to publish in journals that have the highest impact factors which are cited many times per year, Lufkin said, and this is the
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Ependymal Stem Cells May Reverse Paralysis Related to Spinal Cord Injuries

Spinal cord injuries, resulting in permanent disability or paralysis in most cases, account for around eleven thousand new cases in the US, annually. Due to the lack of effective treatment strategies, it is considered as the most devastating of all traumatic conditions. Now, a recent study published in the journal Stem Cells reports that activation of ependymal stem/progenitor cells from injured spinal cord (epSPCi), using endogenous stem cell-associated mechanisms, may aid in rescuing neurological function, thereby reversing paralysis associated with spinal cord injuries.