Tag Archives: Australian Regenerative Medicine Institute

Mapping a route to stem cell therapies

Monash University researchers are shedding light on the complex processes that underpin the creation and differentiation of stem cells, bringing closer the promise of ‘miracle’ therapies.

Dr Jose Polo of the Australian Regenerative Medicine Institute (ARMI) and the Department of Anatomy and Developmental Biology and his team, with collaborators at Harvard, have comprehensively mapped, for the first time, the process by which mature cells are re-programmed to become an induced pluripotent stem (iPS) cell.

iPS cells behave almost exactly like embryonic stem cells – they can become any cell in the body – but come without the ethical and scientific pitfalls.

The
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Stem Cell Therapy for Blindness receives global validation

In 2010, L V Prasad Eye Institute (LVPEI) moved away from culturing corneal stem cells in a petri-dish in the laboratory to directly culturing and expanding them on the patient’s eye.

This ingenuous technique was termed Simple Limbal Epithelial Transplantation (SLET) to contrast it from the radical tissue transplants and complex culture techniques that were the standard of care at that time.

SLET completely eliminates the need for laboratory based processing thereby making it possible to be executed by any well trained surgeon anywhere (…)

A pilot clinical trial was done on a small sample size including 125 patients, 65 adults and 60
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