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Common Virus Kills Breast Cancer Stem Cells

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Dalhousie Medical School cancer researcher Dr. Patrick Lee has proven that a common virus can infect and kill breast cancer stem cells. This breakthrough finding is published in the current issue of Molecular Therapy, the journal of the American Society of Gene Therapy.

It is only within the past few years that the scientific community has understood the full significance of cancer stem cells and the urgent need to find a means of eliminating them.

“Cancer stem cells are essentially mother cells,” explains Dr. Lee, Cameron Chair in Basic Cancer Research at Dalhousie Medical School. “They continuously produce new cancer cells, aggressively forming tumours even when there are only a few of them.”

Cancer stem cells are difficult to kill as they respond poorly to chemotherapy and radiation. As Dr. Lee notes, “You can kill all the regular cancer cells in a tumour, but as long as there are cancer stem cells present, disease will recur.”

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