Tag Archives: American Heart Association

New clinical trial tests efficacy of stem-cell therapy for stroke

An emergency helicopter trip in May that brought a stroke patient from Forrest General Hospital in Hattiesburg landed the Clarke County resident the first spot in a clinical trial at the University of Mississippi Medical Center for stem-cell therapy.

The new therapy could prevent further brain injury following the initial stroke, preserve vital motor and cognitive abilities and shorten recovery times.

The stem-cell treatment also could add a full day to a narrow four-and-a-half-hour window when current drug treatments work best.
The UMMC Comprehensive Stroke Center is one of 10 U.S. sites enrolling a total of 120 patients into the study. The
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Aging heart cells rejuvenated by modified stem cells

Damaged and aged heart tissue of older heart failure External link patients was rejuvenated by stem cells modified by scientists, according to research presented at the American Heart Association’s Basic Cardiovascular Sciences 2012 Scientific Sessions.
The study is simultaneously published in the Journal of the American College of Cardiology.

The research could one day lead to new treatments for heart failure patients, researchers said.

“Since patients with heart failure are normally elderly, their cardiac stem cells aren’t very healthy,” said Sadia Mohsin, Ph.D., one of the study authors and a post-doctoral research scholar at San Diego State University’s Heart Institute
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Nanoparticles plus adult stem cells demolish plaque

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A technique that combines nanotechnology with adult stem cells appears to destroy atherosclerotic plaque and rejuvenate the arteries, according to a study reported at the American Heart Association‘s Basic Cardiovascular Sciences 2010 Scientific Sessions – Technological and Conceptual Advances in Cardiovascular Disease.

In the study, nanoparticles (microscopic particles with at least one dimension less than 80 nm) were infused into the heart of pigs along with adult stem cells. After the nanoparticles were heated by laser light, they burned away arterial plaque. However, nanoparticles were less effective at eliminating plaque if not combined with adult stem cells.

“This unique
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Birth of new cardiac cells

A sophisticated imaging system, multi-isotope imaging mass spectrometry (MIMS), demonstrates cell division in the adult mammalian heart. Researchers were surprised to find that new heart muscle cells primarily arose from existing heart muscle cells, rather than stem cells.

Recent research has shown that there are new cells that develop in the heart, but how these cardiac cells are born and how frequently they are generated remains unclear.

In a study from Harvard-affiliated Brigham and Women’s Hospital (BWH), researchers used a novel method to identify the new heart cells and describe their origins.

The research was published today in Nature.

“The question about how
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Heart attacked helped by Stem Cells from fat

Fat around the waist is commonly seen as a contributing factor to heart attack. Ironically, a company is now testing whether adult stem cells from fat could help prevent long-term damage after a heart attack.

A new medical team is now investigating whether adult stem cells harvested from a person’s own fat, delivered shortly after a heart attack, could prevent some of the cardiac muscle damage that results from blocked arteries.

During a heart attack, blood vessels that deliver blood to the heart muscle are blocked. The lack of oxygen slowly kills the tissue. San Diego-based Cytori Therapeutics has developed
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