Researchers have discovered that umbilical cord stem cells, found in the blood of the umbilical cord, and able to differentiate into various types of tissue, represent a valid treatment alternative for leukemia patients that cannot find a compatible donor for a bone marrow transplant. American hematologists meeting in San Francisco for the 50th American Society of Hematology (ASH) Congress are now focusing their research on these types of stem cells to fight blood borne tumors.
An American study has recently called attention to the possible applications of umbilical cord stem cells for leukemia treatments. For years,
The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research from Johns Hopkins and Harvard.
Although genetically identical to the mature body cells from which they are derived, induced pluripotent stem cells (iPSCs) are notably special in their ability to self-renew and differentiate into all kinds of cells. And now scientists have detected a remarkable if subtle molecular disparity between the two: They have distinct “epigenetic” signatures; that is, they differ in what gets
Many of us remain close to our siblings in adulthood, seeing each other through life’s ups and downs. But for Dr. Don Hicks, director of The Center for Church Relations and Church Health at Liberty Baptist Theological Seminary, and his brother Billy, the relationship couldn’t be closer – they share the same blood and the same immune system. That’s because Don donated his stem cells to his brother last year after discovering he was Billy’s only chance at surviving leukemia.
Billy, who lives in Nashville, Tenn., with his wife and three children (two in high school and one in college),
A Harvard-led team is the first to demonstrate the ability to use low-power light to trigger stem cells inside the body to regenerate tissue, an advance they reported in Science Translational Medicine. The research, led by David J. Mooney, Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences (SEAS), lays the foundation for a host of clinical applications in restorative dentistry and regenerative medicine more broadly, such as wound healing, bone regeneration, and more.
The team used a low-power laser to trigger human dental stem cells to form dentin, the hard tissue that
Scientists have now shown that skin cells can be coaxed to behave like muscle cells and muscle cells like skin cells.
The fickleness of the cells, and the relative ease with which they make the switch, provide a glimpse into the genetic reprogramming that must occur for a cell to become something it’s not.
“We’d all like to understand what happens inside the black box (cell),” said Helen Blau, professor and member of Stanford University‘s Stem Cell Biology and Regenerative Medicine Institute and co-author of a new study on the subject.
Harnessing these genetic makeovers will allow scientists to better