Turn discoveries into stem cell and gene therapies

Stanford announces new Center for Definitive and Curative Medicine

The new Stanford Center for Definitive and Curative Medicine will work to turn discoveries into stem cell and gene therapies to aid the millions of people who have genetic diseases.

At least 280 million people worldwide are living with a rare genetic disease. For many of these millions, the underlying cause of disease is known and well-defined, and yet eludes definitive treatment. At times, surgical interventions, public health measures, biological and small-molecule therapies can transform the health of these populations; often, however, the currently available treatment modalities result in mere palliative, rather
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Stem Cells Against False Joints

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Russian scientists started clinical trials of treating false joints by means of demineralized bone matrix with introduced mesenchymal stem cells of a patient.

False joints often occur as a complication during fractures of long bones, when splinters do not adhere, and cartilage layer forms between them. This layer is called false joint, and in this case, additional surgery is required to help a bone to heal.

Modern surgeons fight this problem with bone transplants, but bone recovery takes about one year. Possible solution is transplantation of mesenchymal stem cells of bone marrow, which can turn into various cells, including
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Skin cells transform to liver cells

In a fresh demonstration of science’s newfound ability to alter the basic units of human life, researchers at the Medical College of Wisconsin have turned the cells in human skin into those in the liver, work that opens new avenues for treating diseases of the liver without relying on organ transplants.

Professor and stem cell researcher Stephen A. Duncan and other scientists in his lab reported this week in the journal Hepatology that they have created reprogrammed mouse liver cells that were identical to those grown in nature and were able to integrate and grow alongside those in a mouse
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ISCO open Its Brand of Human Cell Culture Products for Japanese Markets

International Stem Cell Corporation, announced today its wholly-owned subsidiary, Lifeline Cell Technology (Lifeline), has signed a distribution agreement with Tokyo-based Veritas Corporation to distribute its human cell culture products throughout Japan.

Lifeline, located in Maryland and California, specializes in the development, manufacture, and distribution of products to culture human cells for the study of human disease, including products to culture primary human cells and human stem cells. These products are being requested by customers overseas, including customers in Japan, Korea and India and this agreement is the first step in Lifeline’s plan to meet these requests.

London – Researchers find safer way to make stem cells

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Researchers said on Sunday they had found a safer way to transform ordinary skin cells into powerful stem cells in a move that could eventually remove the need to use human embryos.
It is the first time that scientists have turned skin cells into induced pluripotent stem cells or iPS cells — which look and act like embryonic stem cells — without having to use viruses in the process.
The new method also allows for genes that are inserted to trigger cell reprogramming to be removed afterwards.
Stem cells are the body’s master cells, producing all the body’s tissues and
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