Scientists in the US have made a major breakthrough that has the potential for people with brain damage, caused by epilepsy or Parkinson’s for example, to use their own brain stem cells as a treatment.
Steven Roper of the University of Florida discovered that stem cells from the human brain that were transplanted into the brains of newborn rats matured and were able to function just like native rat cells.
The researchers found that the adult stem cells had the ability to turn into all types of brain tissue in the rats, including the neocortex, which deals with higher processing, and
In a surprise result that can help in the understanding of both aging and cancer, researchers working with an engineered type of stem cell said they reversed the aging process in a rare genetic disease.
The team at Children’s Hospital Boston and the Harvard Stem Cell Institute were working with a new type of cell called induced pluripotent stem cells or iPS cells, which closely resemble embryonic stem cells but are made from ordinary skin cells.
Researchers from the Center for Stem Cell Biology and Regenerative Medicine and the Department of Medicine at Thomas Jefferson University claim that a gene shown to play a role in the aging process appears to play a role in the regulation of the differentiation of embryonic stem cells.
In the study, published online in the journal Aging Cell, the researchers identified a protein interaction that controls the silencing of Oct4, a key transcription factor that is critical to ensuring that embryonic stem cells remain pluripotent. The protein, WRNp, is the product of a gene associated with Werner syndrome, an autosomal
A patient who underwent therapy with knee stem cells one year ago, returned for followup with Dr. Dennis Lox, a Sports and Regenerative Medicine expert who practices in the Tampa Bay, Florida area.
Dr. Lox noted the patient had marked reduction in pain, self reported improvement in functional level (daily tasks that he could perform), and repeat x-rays showed signs of cartilage regrowth. In the academic world, metrics is important. Metrics refers to readily definable measurable improvements. Not self reports of improvements.
X-rays or MRI evidence of repair is a metric. Interestingly, in veterinary medicine the placebo response is not a
Twenty-three local high school students spent their summer vacations in a very unusual place: the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.
The students celebrated their graduations this month from the USC Early Investigator High School (EiHS) and the USC CIRM Science, Technology and Research (STAR) programs. These are the only programs that offer comprehensive training in stem cell research to high school students.
“The goal of these unique programs is to educate bright young minds at the stage where they’re still formulating ideas and still open and receptive to new discoveries, and